GNH USA

Europe — EMA

Imovane

GNH USA supplies Imovane (Zopiclone), a cyclopyrrolone hypnotic for the treatment of insomnia in adults. Request a quote for reliable global supply.

Zopiclone

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What is Zopiclone?

Zopiclone, the active ingredient in Imovane, is a cyclopyrrolone (non‑benzodiazepine hypnotic) presented as an oral tablet for oral use. It is prescribed to manage insomnia in adults by helping patients fall asleep and maintain sleep throughout the night.

GNH USA supplies Imovane as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Zopiclone used for?

Zopiclone is used as a sedative/hypnotic for the treatment of sleep disorders.

Insomnia (sleep onset): facilitates falling asleep quickly. Insomnia (sleep maintenance): reduces nighttime awakenings. Short‑term sleep disturbance: provides temporary relief of difficulty sleeping.

What are the side effects of Zopiclone?

Common Side Effects: - Drowsiness - Dry mouth - Headache - Dizziness - Taste disturbance - Nausea

Serious or Rare Side Effects: - Complex sleep behaviours (e.g., sleepwalking, sleep‑driving) - Severe allergic reactions (rash, swelling, anaphylaxis) - Marked memory impairment or amnesia - Mood changes or depression - Respiratory depression in susceptible individuals

What precautions apply to Zopiclone?

Before prescribing Imovane, clinicians should consider several safety factors. - Assess renal function: adjust use in severe impairment. - Avoid alcohol: may increase sedation and respiratory depression. - Use only short term: limit treatment to 2–4 weeks to reduce dependence risk. - Monitor for dependence: discontinue gradually under medical supervision. - Pregnancy and lactation: consult a physician before use. - Store at ambient temperature: keep in original container, protect from moisture and light.

What does Zopiclone interact with?

Zopiclone may interact with other substances that depress the central nervous system.

Major Interactions (Avoid): - Alcohol: additive CNS depression and increased sedation. - Opioids: heightened risk of respiratory depression. - Other CNS depressants (e.g., benzodiazepines, antihistamines): enhanced sedative effect.

Moderate Interactions (Monitor Closely): - CYP3A4 inhibitors (e.g., ketoconazole): may raise plasma concentrations. - CYP3A4 inducers (e.g., rifampicin): may reduce therapeutic effect. - Certain antidepressants (e.g., fluoxetine): can increase sedation and prolong half‑life.

Frequently asked questions

What is Imovane used for?+
Imovane contains zopiclone, which is indicated for the short‑term management of insomnia. It helps adults who have difficulty falling asleep or staying asleep, providing a pharmacologic option to improve sleep quality under medical supervision.
How does zopiclone work?+
Zopiclone acts as a positive allosteric modulator at the GABA_A receptor complex. By binding to a specific site, it enhances GABA’s inhibitory action, increasing chloride influx into neurons, which depresses central nervous system activity and promotes sleep.
What is the usual dose of Imovane?+
The appropriate dose of Imovane is determined by the prescribing clinician based on individual factors such as age, renal function, and severity of insomnia. Dosage may be adjusted for elderly or hepatic‑impaired patients, and treatment is generally limited to a short duration.
Is Imovane safe in pregnancy or breastfeeding?+
Safety of zopiclone during pregnancy or lactation has not been definitively established. Healthcare providers usually advise avoiding its use in pregnant or nursing women unless the potential benefit outweighs the risk, and they often recommend non‑pharmacologic sleep strategies instead.
How do I order Imovane from GNH USA?+
To place an order, submit an enquiry on the Imovane product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Imovane compare with other sleep aids?+
Compared with benzodiazepine hypnotics, zopiclone belongs to the cyclopyrrolone class and generally has a shorter half‑life and a lower risk of dependence, although tolerance can still develop. It is often preferred when a non‑benzodiazepine option is desired for short‑term insomnia treatment.
How should Imovane be stored?+
Imovane tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and avoid storing in humid environments such as bathrooms.
How is Imovane administered?+
Imovane is taken orally, usually shortly before bedtime, after ensuring a full night’s sleep opportunity of 7–8 hours. The tablet should be swallowed whole with a glass of water and not be taken with or after a large meal that could delay absorption.
What are the most serious risks to watch for?+
Serious adverse reactions to zopiclone, though uncommon, include complex sleep behaviours such as sleepwalking or sleep‑driving, severe allergic reactions, and marked memory impairment. Patients should seek immediate medical attention if they experience unusual activities while asleep or signs of an allergic response.
Who should not use Imovane?+
Imovane is contraindicated in individuals with known hypersensitivity to zopiclone or other cyclopyrrolones, patients with severe hepatic impairment, and those with a history of substance dependence. Caution is also advised for elderly patients and those with existing respiratory depression.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Zopiclone
Route
Oral Use
Manufacturer
Sanofi Romania Srl
Origin
EU

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