GNH USA

Europe — EMA

Imodium Plus

GNH USA supplies Imodium Plus (Loperamide & Dimeticone), an antidiarrheal for acute and chronic diarrhea and gas relief. Request a quote for worldwide supply.

Dimeticone, Loperamide Hydrochloride

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1
Pack/s

What is Dimeticone, Loperamide Hydrochloride?

Loperamide Hydrochloride and Dimeticone, the active ingredient in Imodium Plus, is an antidiarrheal and antifoaming presented as an oral tablet for oral use. It treats acute and travel‑related diarrhea as well as gas‑related discomfort in adults and children.

GNH USA supplies Imodium Plus as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Dimeticone, Loperamide Hydrochloride used for?

Imodium Plus is indicated for conditions affecting intestinal motility and gas accumulation. - Acute diarrhea: provides symptomatic relief by slowing gut transit. - Travelers' diarrhea: reduces stool frequency and urgency during travel‑related infections. - Chronic diarrhea: helps manage persistent loose stools in conditions such as IBS‑D. - Gas relief: alleviates abdominal bloating by reducing surface tension of gas bubbles.

What are the side effects of Dimeticone, Loperamide Hydrochloride?

Imodium Plus may cause a range of adverse reactions, most of which are mild and transient. Common Side Effects: - Constipation: excessive slowing of bowel movements. - Nausea: mild stomach upset. - Abdominal cramps: intermittent discomfort. Serious or Rare Side Effects: - Severe constipation: risk of bowel obstruction. - Toxic megacolon: rare but life‑threatening colonic dilation. - Allergic reactions: rash, itching, swelling.

What precautions apply to Dimeticone, Loperamide Hydrochloride?

Before using Imodium Plus, consider the following precautions. - Pregnancy: safety not established; use only if clearly needed. - Breastfeeding: unknown; weigh benefits versus risks. - Age restrictions: not recommended for children under 2 years. - Medical conditions: avoid in patients with known intestinal obstruction or severe hepatic impairment. - Drug interactions: consult a healthcare professional before combining with other antidiarrheals or opioids. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

What does Dimeticone, Loperamide Hydrochloride interact with?

Imodium Plus can interact with several medicines; review the categories below. Major Interactions (Avoid): - Concomitant use with other opioid agonists: may enhance central opioid effects. - Strong CYP3A4 inhibitors (e.g., clarithromycin, itraconazole): increase loperamide plasma levels. - Anticholinergic agents: may exacerbate constipation. Moderate Interactions (Monitor Closely): - Other antidiarrheal agents (e.g., bismuth subsalicylate): may reduce overall efficacy. - Drugs that prolong QT interval: additive cardiac risk. - Herbal supplements containing senna or cascara: increase risk of bowel dysfunction.

Frequently asked questions

What is Imodium Plus used for?+
Imodium Plus is used to relieve symptoms of acute, travel‑related and chronic diarrhea as well as to reduce abdominal bloating and gas. The combination of loperamide and dimeticone targets both excessive bowel movements and trapped gas in the gastrointestinal tract.
How does Loperamide Hydrochloride work?+
Loperamide Hydrochloride activates µ‑opioid receptors in the intestinal wall, which slows peristalsis and increases the time for water absorption. This results in firmer stools and fewer bowel movements, helping control diarrhea.
What is the usual dose of Imodium Plus?+
The appropriate dose of Imodium Plus is determined by a prescriber based on the patient’s age, severity of symptoms, and clinical condition. Patients should follow the healthcare professional’s instructions and not exceed the recommended amount.
Is Imodium Plus safe during pregnancy or breastfeeding?+
Safety data for Imodium Plus in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.
How do I order Imodium Plus from GNH USA?+
To order Imodium Plus, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Imodium Plus compare with other antidiarrheal drugs?+
Compared with single‑ingredient loperamide products, Imodium Plus adds dimeticone, which helps relieve gas and bloating. This dual action can be advantageous for patients who experience both diarrhea and abdominal discomfort, whereas standard loperamide addresses only stool frequency.
How should Imodium Plus be stored and handled?+
Imodium Plus should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the tablets away from moisture, direct sunlight and heat sources to maintain product stability.
How is Imodium Plus administered?+
Imodium Plus is taken orally, usually with a glass of water. The tablet should be swallowed whole and not chewed or crushed, unless otherwise directed by a healthcare professional.
What are the most serious risks associated with Imodium Plus?+
Serious risks include severe constipation that can lead to bowel obstruction, toxic megacolon in susceptible individuals, and rare allergic reactions such as rash or swelling. Patients should seek immediate medical attention if they experience these symptoms.
Who should not use Imodium Plus?+
Imodium Plus should be avoided in children under two years of age, individuals with known intestinal blockage, severe hepatic impairment, or those taking strong CYP3A4 inhibitors without medical supervision. Consultation with a healthcare provider is essential before use in these populations.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Dimeticone, Loperamide Hydrochloride
Route
Oral Use
Manufacturer
Mcneil Healthcare (Ireland) Limited
Origin
EU

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