Europe — EMA
Imodium Instant
GNH USA supplies Imodium Instant (Loperamide Hydrochloride), an opioid antidiarrheal for acute nonspecific diarrhea, traveler's diarrhea, and chronic
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What is Loperamide Hydrochloride?
Loperamide Hydrochloride, the active ingredient in Imodium Instant, is an opioid antidiarrheal presented as an oral tablet for oral use. It treats acute nonspecific diarrhea, traveler's diarrhea, and chronic diarrhea in adults and children. GNH USA supplies Imodium Instant as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Loperamide Hydrochloride used for?
Imodium Instant, an opioid antidiarrheal, is used to manage conditions that increase intestinal motility and fluid loss.
Acute nonspecific diarrhea: reduces stool frequency and improves consistency. Traveler's diarrhea: provides rapid symptom relief for travelers experiencing sudden loose stools. Chronic diarrhea: helps control ongoing diarrheal episodes in conditions such as irritable bowel syndrome with diarrhea.
What are the side effects of Loperamide Hydrochloride?
Common Side Effects: - Constipation: reduced bowel movements may become overly firm. - Abdominal cramps: mild discomfort or cramping in the abdomen. - Nausea: occasional feeling of queasiness. - Dizziness: transient light‑headed sensation.
Serious or Rare Side Effects: - Severe constipation or intestinal obstruction: may require medical attention. - Toxic megacolon: rare but life‑threatening dilation of the colon. - Allergic reactions: rash, swelling, or hives. - Cardiac arrhythmia: abnormal heart rhythm, especially at high doses.
What precautions apply to Loperamide Hydrochloride?
Before using Imodium Instant, consider the following precautions.
Dose adjustment in hepatic impairment: reduce dose as recommended by a healthcare professional. Avoid in children under 2 years: not indicated for this age group. Do not use with known hypersensitivity to loperamide or excipients. Caution with concurrent use of other opioids: may increase central opioid effects. Store at ambient temperature: keep in the original pack, protect from moisture.
What does Loperamide Hydrochloride interact with?
Imodium Instant may interact with other medicines. Review the following.
Major Interactions (Avoid): - CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): may raise loperamide plasma levels. - CYP2C8 inhibitors (e.g., gemfibrozil): increase risk of toxicity. - Other antidiarrheals (e.g., diphenoxylate): additive slowing of gut motility.
Moderate Interactions (Monitor Closely): - CNS depressants (e.g., benzodiazepines): may enhance sedation. - Anticholinergic agents: may exacerbate constipation. - QT‑prolonging drugs: monitor cardiac rhythm for arrhythmia risk.
Frequently asked questions
What is Imodium Instant used for?+
How does Loperamide Hydrochloride work?+
What is the usual dose of Imodium Instant?+
Is Imodium Instant safe during pregnancy or breastfeeding?+
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How does Imodium Instant compare with other antidiarrheal agents?+
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Who should not use Imodium Instant?+
Product details
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