GNH USA

Europe — EMA

Imodium Akut

GNH USA supplies Imodium Akut (Loperamide Hydrochloride), an opioid antidiarrheal for acute and travel‑related diarrhea. Request a quote for global supply.

Loperamide Hydrochloride

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1
Pack/s

What is Loperamide Hydrochloride?

Loperamide Hydrochloride, the active ingredient in Imodium Akut, is a opioid antidiarrheal presented as a tablet for oral use. It treats acute nonspecific diarrhea, traveler’s diarrhea, and chronic diarrhea associated with inflammatory bowel disease in adults.

GNH USA supplies Imodium Akut as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Loperamide Hydrochloride used for?

Imodium Akut (loperamide) is used to manage diarrheal conditions by reducing intestinal motility.

Acute nonspecific diarrhea: reduces stool frequency and improves consistency. Traveler's diarrhea: provides symptomatic relief during short‑term travel‑related episodes. Chronic diarrhea associated with inflammatory bowel disease: helps control stool output in IBD patients.

What are the side effects of Loperamide Hydrochloride?

Common Side Effects: - Abdominal cramps - Constipation - Nausea - Dizziness

Serious or Rare Side Effects: - Severe constipation or paralytic ileus - Allergic reactions such as rash or swelling - Cardiac arrhythmias (e.g., QT prolongation)

What precautions apply to Loperamide Hydrochloride?

Before using Imodium Akut, consider the following precautions: - Assess underlying cause: ensure diarrhea is not due to an infection requiring antibiotics. - Avoid use in children under 2 years: not recommended for very young patients. - Limit duration: do not exceed 48 hours without medical review. - Monitor for dehydration: maintain adequate fluid intake. - Store at ambient temperature: keep below 25°C in the original pack, protect from moisture.

What does Loperamide Hydrochloride interact with?

Imodium Akut may interact with other medicines as follows:

Major Interactions (Avoid): - Concomitant use with potent CYP3A4 inhibitors (e.g., ketoconazole) may increase loperamide levels. - Co‑administration with other opioid agonists can enhance central opioid effects. - Use with quinidine may raise plasma concentrations.

Moderate Interactions (Monitor Closely): - CYP2C8 inhibitors (e.g., gemfibrozil) may modestly increase exposure. - Anticholinergic agents may exacerbate constipation. - Certain antidiarrheal combinations (e.g., diphenoxylate) may increase risk of adverse effects.

Frequently asked questions

What is Imodium Akut used for?+
Imodium Akut is an over‑the‑counter antidiarrheal medication used to relieve symptoms of acute nonspecific diarrhea, traveler’s diarrhea, and chronic diarrhea associated with inflammatory bowel disease. It works by slowing intestinal transit, which reduces stool frequency and improves consistency.
How does loperamide work?+
Loperamide acts as a peripheral μ‑opioid receptor agonist in the gut. By binding to these receptors, it decreases smooth‑muscle activity, slows the movement of contents through the intestines, and promotes absorption of water and electrolytes, resulting in firmer stools and fewer bowel movements.
What is the usual dose of Imodium Akut?+
The appropriate dose of Imodium Akut is determined by a healthcare professional based on the individual’s condition, age, and response to therapy. Patients should follow the prescriber’s instructions and the product labeling, and should not exceed the recommended amount without medical advice.
Is Imodium Akut safe in pregnancy or breastfeeding?+
Safety data for loperamide during pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their healthcare provider before using Imodium Akut to weigh potential benefits against possible risks.
How do I order Imodium Akut from GNH USA?+
To order Imodium Akut, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.
How does Imodium Akut compare with the main alternative drug?+
The primary alternative to loperamide is diphenoxylate‑atropine (Lomotil). Both reduce intestinal motility, but diphenoxylate has central opioid activity that may cause more sedation, while loperamide remains largely peripheral, offering a lower risk of central opioid effects. Choice depends on clinical judgment and patient tolerance.
How should Imodium Akut be stored and handled?+
Imodium Akut tablets should be stored at ambient temperature, below 25 °C. Keep them in the original container, protect from moisture and direct sunlight, and keep out of reach of children. Do not use if the packaging is damaged or the tablets appear discolored.
How is Imodium Akut administered?+
Imodium Akut is taken orally with a glass of water. The first dose is usually taken after the first loose stool, and subsequent doses may be taken after each additional loose stool, not exceeding the maximum daily amount recommended by a healthcare professional.
What are the most serious risks to watch for while taking Imodium Akut?+
Serious risks include severe constipation, paralytic ileus, toxic megacolon, and allergic reactions such as rash, swelling or anaphylaxis. If any of these occur, stop the medication immediately and seek medical attention.
Who should not use Imodium Akut?+
Imodium Akut should not be used by children younger than 2 years, individuals with bacterial dysentery, pseudomembranous colitis, or known hypersensitivity to loperamide or any tablet excipients. Patients with severe liver disease should also avoid use unless directed by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Loperamide Hydrochloride
Route
Oral Use
Manufacturer
Kenvue Germany Gmbh
Origin
EU

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