Europe — EMA
Imodium Akut
GNH USA supplies Imodium Akut (Loperamide Hydrochloride), an opioid antidiarrheal for acute and travel‑related diarrhea. Request a quote for global supply.
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What is Loperamide Hydrochloride?
Loperamide Hydrochloride, the active ingredient in Imodium Akut, is a opioid antidiarrheal presented as a tablet for oral use. It treats acute nonspecific diarrhea, traveler’s diarrhea, and chronic diarrhea associated with inflammatory bowel disease in adults.
GNH USA supplies Imodium Akut as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Loperamide Hydrochloride used for?
Imodium Akut (loperamide) is used to manage diarrheal conditions by reducing intestinal motility.
Acute nonspecific diarrhea: reduces stool frequency and improves consistency. Traveler's diarrhea: provides symptomatic relief during short‑term travel‑related episodes. Chronic diarrhea associated with inflammatory bowel disease: helps control stool output in IBD patients.
What are the side effects of Loperamide Hydrochloride?
Common Side Effects: - Abdominal cramps - Constipation - Nausea - Dizziness
Serious or Rare Side Effects: - Severe constipation or paralytic ileus - Allergic reactions such as rash or swelling - Cardiac arrhythmias (e.g., QT prolongation)
What precautions apply to Loperamide Hydrochloride?
Before using Imodium Akut, consider the following precautions: - Assess underlying cause: ensure diarrhea is not due to an infection requiring antibiotics. - Avoid use in children under 2 years: not recommended for very young patients. - Limit duration: do not exceed 48 hours without medical review. - Monitor for dehydration: maintain adequate fluid intake. - Store at ambient temperature: keep below 25°C in the original pack, protect from moisture.
What does Loperamide Hydrochloride interact with?
Imodium Akut may interact with other medicines as follows:
Major Interactions (Avoid): - Concomitant use with potent CYP3A4 inhibitors (e.g., ketoconazole) may increase loperamide levels. - Co‑administration with other opioid agonists can enhance central opioid effects. - Use with quinidine may raise plasma concentrations.
Moderate Interactions (Monitor Closely): - CYP2C8 inhibitors (e.g., gemfibrozil) may modestly increase exposure. - Anticholinergic agents may exacerbate constipation. - Certain antidiarrheal combinations (e.g., diphenoxylate) may increase risk of adverse effects.
Frequently asked questions
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Product details
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