GNH USA

Europe — EMA

Imidazyl

GNH USA supplies Imidazyl (Naphazoline Nitrate), an alpha‑adrenergic ocular decongestant for fast relief of eye redness. Request a quote for global supply.

Naphazoline Nitrate

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What is Naphazoline Nitrate?

Naphazoline Nitrate, the active ingredient in Imidazyl, is a alpha‑adrenergic agonist presented as an eye drop for ocular use. It reduces conjunctival redness and swelling in adults and children. GNH USA supplies Imidazyl as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Naphazoline Nitrate used for?

Imidazyl is an ocular decongestant that acts on the conjunctival vasculature to alleviate redness and swelling. - Ocular redness: provides rapid reduction of visible redness by constricting conjunctival blood vessels. - Conjunctival hyperemia: diminishes vessel dilation, improving eye appearance and comfort. - Eye irritation due to minor inflammation: helps relieve mild swelling and redness associated with irritants.

What are the side effects of Naphazoline Nitrate?

Imidazyl may cause a range of ocular and systemic reactions.

Common Side Effects: - Stinging or burning sensation upon instillation. - Transient blurred vision. - Mild eye itching or dryness. - Temporary headache.

Serious or Rare Side Effects: - Increased intra‑ocular pressure, especially in glaucoma patients. - Severe allergic reaction (e.g., swelling, rash, difficulty breathing). - Corneal ulceration or persistent eye pain.

What precautions apply to Naphazoline Nitrate?

Use Imidazyl with care and observe the following precautions. - Avoid use in patients with narrow‑angle glaucoma: risk of elevated intra‑ocular pressure. - Do not use if known hypersensitivity to naphazoline or any excipient: may trigger allergic response. - Limit application to 3‑4 times daily: prolonged use can cause rebound redness. - Do not apply to infected, ulcerated, or severely inflamed eyes: may worsen condition. - Store at room temperature: keep in the original container, protect from light and moisture.

What does Naphazoline Nitrate interact with?

Imidazyl can interact with other medications affecting vascular tone.

Major Interactions (Avoid): - Concurrent use with MAO inhibitors: may potentiate vasoconstrictive effects. - Use with other ocular decongestants: risk of additive vasoconstriction. - Combination with sympathomimetic eye drops: may cause excessive vasoconstriction.

Moderate Interactions (Monitor Closely): - Use with topical anesthetics: may increase corneal toxicity. - Concurrent systemic alpha‑adrenergic agonists: monitor blood pressure for additive effects.

Frequently asked questions

What is Imidazyl used for?+
Imidazyl is an over‑the‑counter eye drop used to relieve ocular redness and mild swelling caused by conjunctival hyperemia or minor irritation. It works by constricting the small blood vessels on the surface of the eye, providing rapid cosmetic and symptomatic improvement.
How does Naphazoline Nitrate work?+
Naphazoline Nitrate is a selective alpha‑adrenergic receptor agonist. When applied to the eye, it binds to alpha receptors on conjunctival vessels, causing vasoconstriction. This reduces blood flow to the ocular surface, decreasing capillary dilation, redness, and associated swelling.
What is the usual dose of Imidazyl?+
The appropriate dosing regimen for Imidazyl is determined by the prescribing healthcare professional. Typically, one or two drops are instilled in the affected eye(s) up to three to four times per day, but the exact frequency and duration should follow the prescriber’s instructions.
Is Imidazyl safe during pregnancy or breastfeeding?+
Safety data for Naphazoline Nitrate in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.
How do I order Imidazyl from GNH USA?+
To order Imidazyl, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Imidazyl compare with other ocular decongestants such as tetrahydrozoline?+
Both Imidazyl (naphazoline nitrate) and tetrahydrozoline are alpha‑adrenergic agonists that reduce eye redness through vasoconstriction. Naphazoline generally has a slightly faster onset, while tetrahydrozoline may have a longer duration of action. Choice of product depends on clinician preference, patient response, and formulation availability.
How should Imidazyl be stored and handled?+
Imidazyl should be stored at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed when not in use and retain it in its original packaging to protect the formulation from contamination.
How is Imidazyl administered?+
Imidazyl is administered topically as eye drops. The patient should wash hands, tilt the head back, pull down the lower eyelid, and place the prescribed number of drops into the conjunctival sac. Avoid touching the tip of the bottle to the eye or any surface.
What are the most serious risks associated with Imidazyl?+
Serious risks include a rise in intra‑ocular pressure, especially in patients with narrow‑angle glaucoma, and rare allergic reactions that may cause swelling, rash, or breathing difficulties. Persistent eye pain or vision changes should prompt immediate medical evaluation.
Who should not use Imidazyl?+
Imidazyl should not be used by individuals with known hypersensitivity to naphazoline nitrate or any excipients, and it is contraindicated in eyes with narrow‑angle glaucoma, severe ocular infection, or ulceration. Patients with these conditions should consult a healthcare professional for alternative therapy.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Naphazoline Nitrate
Route
Ocular Use
Manufacturer
Recordati Industria Chimica E Farmaceutica S.P.A.
Origin
EU

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