Imdur

Isosorbide Mononitrate, the active ingredient in Imdur, is a nitrate vasodilator presented as an oral tablet for oral use. It is employed to prevent angina pectoris and to manage chronic stable angina in adult patients.

GNH USA supplies Imdur as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Imdur belongs to the nitrate vasodilator class and is used in the management of angina‑related conditions. - Prevention of angina pectoris: reduces the frequency of angina attacks in patients with chronic stable angina. - Chronic stable angina: improves exercise tolerance and decreases myocardial oxygen demand. - Angina pectoris (symptomatic relief): alleviates chest pain during episodes of myocardial ischemia.

Common Side Effects: - Headache: mild to moderate throbbing sensation. - Dizziness: sensation of light‑headedness, especially on standing. - Flushing: warm feeling and reddening of the skin. - Hypotension: lower than normal blood pressure readings. - Nausea: mild gastrointestinal upset. - Palpitations: awareness of heartbeats.

Serious or Rare Side Effects: - Severe hypotension: marked drop in blood pressure requiring medical attention. - Syncope: sudden loss of consciousness. - Myocardial infarction: rare occurrence of heart attack. - Allergic reaction: rash, itching, swelling, or difficulty breathing. - Stevens‑Johnson syndrome: severe skin reaction, extremely rare.

Before initiating therapy, clinicians should consider several safety aspects. - Assess cardiovascular status: evaluate blood pressure and heart function prior to use. - Avoid concurrent PDE‑5 inhibitors: risk of profound hypotension. - Monitor for tolerance development: adjust therapy if efficacy diminishes. - Use with caution in hepatic or renal impairment: consider dose modification. - Store at ambient temperature: keep below 25°C, retain original packaging and protect from moisture.

Isosorbide Mononitrate can interact with several drug classes. Major Interactions (Avoid): - Sildenafil and other PDE‑5 inhibitors: may cause severe hypotension. - Other nitrates (e.g., nitroglycerin): additive vasodilatory effect leading to dangerous blood pressure drop. - Antihypertensive agents (ACE inhibitors, beta‑blockers): may enhance blood pressure lowering. Moderate Interactions (Monitor Closely): - Diuretics: may increase risk of orthostatic hypotension. - Alcohol: can potentiate vasodilatory effects and dizziness.