Imazol

Clotrimazole, the active ingredient in Imazol, is an azole antifungal presented as a topical preparation for skin application. It treats superficial fungal infections such as dermatophyte infections, candidiasis of the skin and mucous membranes, and seborrheic dermatitis, and is intended for use in adults and children when appropriate.

GNH USA supplies Imazol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for each batch, ensuring reliable supply across multiple regions.

Clotrimazole is used to treat fungal skin conditions by targeting the organisms that cause dermatophyte and yeast infections.

- Dermatophyte infections (tinea corporis, tinea cruris, tinea pedis): reduces fungal growth and alleviates itching, redness and scaling. - Cutaneous candidiasis: eliminates Candida species on skin and mucous membranes, improving lesions and discomfort. - Seborrheic dermatitis: controls Malassezia‑related inflammation, decreasing flaking and erythema.

Clotrimazole is generally well tolerated, but topical application can cause local skin reactions.

Common Side Effects: - Skin irritation: mild burning or stinging. - Itching: transient pruritus. - Redness: localized erythema.

Serious or Rare Side Effects: - Allergic contact dermatitis: swelling, blistering or hives. - Angioedema: rapid swelling of face, lips or tongue. - Stevens‑Johnson syndrome: severe skin reaction, extremely rare.

When using Imazol, certain precautions help minimize adverse reactions and ensure safe application.

- Avoid application on broken or inflamed skin: may increase irritation. - Discontinue use if severe redness or swelling occurs: seek medical advice. - Keep away from eyes, ears and mucous membranes: avoid accidental contact. - Do not use on infants under one month of age: safety not established. - Do not combine with potent topical corticosteroids without guidance: may mask infection. - Store at room temperature: keep in original container, protect from moisture and light.

Clotrimazole has a low potential for systemic drug interactions, but topical use can be affected by other agents applied to the same area.

Major Interactions (Avoid): - Concurrent systemic azole antifungals (e.g., fluconazole): may increase systemic exposure if large skin areas are treated. - Use with occlusive dressings: enhances absorption and can raise risk of irritation.

Moderate Interactions (Monitor Closely): - Co‑application with topical corticosteroids: may reduce antifungal efficacy or mask infection signs. - Use with other irritant skin products (e.g., alcohol‑based cleansers): may increase local irritation. - Combination with other topical antifungals: monitor for additive skin reactions.