GNH USA

Europe — EMA

Ilyssa

GNH USA supplies Ilyssa (Drospirenone/Ethinylestradiol), a combined oral contraceptive for pregnancy prevention and menstrual regulation.

Drospirenone, Ethinylestradiol | Lactose Anhydrous

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What is Drospirenone, Ethinylestradiol | Lactose Anhydrous?

Drospirenone/Ethinylestradiol, the active ingredient in Ilyssa, is a combined oral contraceptive presented as a tablet for oral use. It prevents pregnancy and can help regulate menstrual cycles in women of reproductive age. Ilyssa is marketed in the European Union and complies with relevant regulatory standards for hormonal contraceptives.

GNH USA supplies Ilyssa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Drospirenone, Ethinylestradiol | Lactose Anhydrous used for?

Ilyssa, a combined oral contraceptive, acts on the hormonal regulation of the menstrual cycle.

Contraception: provides effective prevention of pregnancy when taken as directed. Regulation of menstrual cycles: helps achieve more predictable bleeding patterns. Management of acne: may improve acne associated with androgen excess in women.

What are the side effects of Drospirenone, Ethinylestradiol | Lactose Anhydrous?

Ilyssa may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Nausea: mild stomach upset that often resolves with continued use. - Headache: occasional tension‑type or migraine‑type headaches. - Breast tenderness: temporary swelling or discomfort. - Breakthrough bleeding: spotting between periods, especially during the first months. - Weight fluctuation: minor changes in fluid retention. - Mood changes: irritability or mild mood swings.

Serious or Rare Side Effects: - Venous thromboembolism: blood clots in deep veins or lungs, requiring immediate medical attention. - Hypertension: significant increase in blood pressure. - Liver dysfunction: abnormal liver enzyme levels or jaundice. - Allergic reaction: rash, swelling, or difficulty breathing. - Gallbladder disease: rare occurrence of gallstones or inflammation.

What precautions apply to Drospirenone, Ethinylestradiol | Lactose Anhydrous?

Before prescribing Ilyssa, clinicians should assess individual risk factors and contraindications.

Cardiovascular risk assessment: evaluate history of thrombosis, smoking, or hypertension. Pregnancy status: confirm the patient is not pregnant before initiating therapy. Liver disease: avoid use in active liver disease or severe hepatic impairment. Migraine with aura: contraindicated in patients with migraine accompanied by neurological symptoms. Age >35 and smoking: contraindicated for women over 35 who smoke. Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

What does Drospirenone, Ethinylestradiol | Lactose Anhydrous interact with?

Ilyssa can interact with several medicines, altering its efficacy or safety profile.

Major Interactions (Avoid): - Antiepileptic drugs (e.g., carbamazepine, phenytoin): may reduce contraceptive effectiveness. - Rifampin and other potent enzyme inducers: can markedly decrease hormone levels. - Certain HIV protease inhibitors: may increase hormone concentrations, raising risk of side effects.

Moderate Interactions (Monitor Closely): - Antifungal agents (e.g., ketoconazole): may increase hormone levels. - St. John’s wort: may modestly reduce contraceptive efficacy. - Certain antibiotics (e.g., clarithromycin): potential modest effect on hormone metabolism. - Diuretics: may affect fluid balance and blood pressure, requiring monitoring.

Frequently asked questions

What is Ilyssa used for?+
Ilyssa is a combined oral contraceptive containing drospirenone and ethinylestradiol. It is primarily prescribed to prevent pregnancy and can also help regulate menstrual cycles and improve acne associated with androgen excess in women of reproductive age.
How does drospirenone/ethinylestradiol work?+
The combination suppresses the mid‑cycle surge of luteinising hormone (LH) and follicle‑stimulating hormone (FSH), preventing ovulation. Drospirenone also thickens cervical mucus to block sperm, while ethinylestradiol stabilises the endometrial lining, reducing the chance of implantation.
What is the usual dose of Ilyssa?+
The dosing regimen for Ilyssa is determined by the prescribing clinician. Typically, it is taken once daily at the same time each day, but the exact schedule and duration should follow the healthcare provider’s instructions.
Is Ilyssa safe to use during pregnancy or breastfeeding?+
Ilyssa is contraindicated during pregnancy because it is intended to prevent conception. If pregnancy occurs, the medication should be stopped immediately. Safety during breastfeeding has not been established; women should discuss alternatives with their healthcare professional.
How do I order Ilyssa from GNH USA?+
To order Ilyssa, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Ilyssa compare with other combined oral contraceptives?+
Ilyssa contains drospirenone, a progestin with anti‑androgenic and mild diuretic properties, which may offer advantages in reducing water retention and acne compared with some other progestins. Its efficacy in preventing pregnancy is comparable to other combined oral contraceptives, but individual tolerability can vary.
What are the storage requirements for Ilyssa?+
Ilyssa tablets should be stored at ambient temperature, below 25 °C. Keep them in the original blister pack, protect from moisture and direct sunlight, and ensure they are out of reach of children.
How is Ilyssa administered?+
Ilyssa is taken orally, usually as a single tablet each day at the same time. The typical regimen follows a 21‑day active tablet sequence followed by a 7‑day placebo or hormone‑free interval, but patients should follow the schedule prescribed by their clinician.
What are the most serious risks associated with Ilyssa?+
Serious risks include venous thromboembolism, arterial thrombosis, hypertension, liver dysfunction, and rare allergic reactions. Women with a history of clotting disorders, smoking over age 35, or certain cardiovascular conditions should avoid using Ilyssa.
Who should not use Ilyssa?+
Ilyssa is contraindicated in women who are pregnant, have a history of thromboembolic disease, uncontrolled hypertension, severe liver disease, known or suspected breast cancer, or who smoke cigarettes and are over 35 years of age. It should also be avoided in individuals with migraine with aura.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Drospirenone, Ethinylestradiol | Lactose Anhydrous
Route
Oral Use
Manufacturer
Crescent Pharma Limited
Origin
EU

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