GNH USA

Europe — EMA

Iloprost Teva

GNH USA supplies Iloprost Teva (Iloprost), a prostacyclin analog for pulmonary arterial hypertension. Request a quote for global supply to qualified buyers.

Iloprost

Request sourcing

1
Pack/s

What is Iloprost?

Iloprost, the active ingredient in Iloprost Teva, is a prostacyclin analog presented as a solution for injection for intravenous or subcutaneous use. It treats pulmonary arterial hypertension in adult patients by promoting vasodilation and inhibiting platelet aggregation. GNH USA supplies Iloprost Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

What is Iloprost used for?

Iloprost is a prostacyclin analog used in the management of pulmonary arterial hypertension, a condition characterized by elevated pulmonary vascular resistance.

Pulmonary arterial hypertension: improves exercise capacity and delays disease progression.

What are the side effects of Iloprost?

Iloprost may cause a range of adverse reactions.

Common Side Effects: - Flushing: transient warmth and redness of the skin. - Headache: mild to moderate intensity. - Jaw pain: discomfort during chewing. - Nausea: occasional upset stomach. - Diarrhea: loose stools. - Hypotension: mild drop in blood pressure.

Serious or Rare Side Effects: - Severe hypotension: marked blood pressure fall requiring intervention. - Pulmonary edema: fluid accumulation in lungs. - Bleeding: increased risk due to antiplatelet effect. - Thrombocytopenia: low platelet count. - Injection‑site infection: redness or pus at administration site. - Chest pain: angina‑like discomfort.

What precautions apply to Iloprost?

Before initiating Iloprost therapy, several safety considerations are recommended. - Renal impairment: monitor renal function and adjust therapy as needed. - Hepatic impairment: use with caution and observe liver enzymes. - Pregnancy: risk unknown; avoid unless benefits outweigh risks. - Bleeding disorders: assess bleeding risk before treatment. - Concomitant vasodilators: monitor blood pressure closely. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Iloprost interact with?

Iloprost can interact with other medications, requiring careful management.

Major Interactions (Avoid): - Epoprostenol: additive vasodilation may cause severe hypotension. - Sildenafil: combined effect can lead to dangerous blood pressure drops. - Warfarin: enhanced antiplatelet activity may increase bleeding risk.

Moderate Interactions (Monitor Closely): - Calcium channel blockers: monitor for additive hypotensive effect. - Beta‑blockers: may mask signs of low blood pressure. - Other prostacyclin analogs: risk of cumulative vasodilatory effects.

Frequently asked questions

What is Iloprost Teva used for?+
Iloprost Teva is indicated for the treatment of pulmonary arterial hypertension (PAH). It helps lower elevated pulmonary arterial pressure, improves exercise capacity, and may delay disease progression in adult patients with this serious vascular condition.
How does Iloprost work?+
Iloprost acts as a selective agonist of the prostacyclin (IP) receptor on vascular smooth‑muscle cells. Activation increases cyclic AMP, causing potent vasodilation of pulmonary arteries and inhibition of platelet aggregation, which together reduce pulmonary arterial pressure.
What is the usual dose of Iloprost?+
The dosing regimen for Iloprost is individualized. A qualified prescriber determines the appropriate dose, infusion rate, and duration based on the patient’s clinical status, response, and tolerance. Specific dosing details should be obtained from the treating physician.
Is Iloprost safe in pregnancy or breastfeeding?+
Safety data for Iloprost during pregnancy and lactation are limited. The drug should be used only if the potential benefit justifies the potential risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.
How do I order Iloprost Teva from GNH USA?+
To order Iloprost Teva, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies, and procurement teams worldwide. After verification of trade or institutional credentials, the sales team will provide pricing, availability, shipping details (including cold‑chain if needed), and import documentation.
How does Iloprost compare with other prostacyclin therapies?+
Iloprost is a prostacyclin analog similar to epoprostenol and treprostinil but differs in pharmacokinetics and administration. Compared with epoprostenol, Iloprost has a longer half‑life and can be given subcutaneously, offering more flexible dosing. Treprostinil also provides oral and inhaled forms, whereas Iloprost is available only as an injectable solution.
What are the storage and handling requirements for Iloprost?+
Iloprost solution for injection must be stored refrigerated at 2‑8 °C. Protect it from light, do not freeze, and avoid shaking the vial. Keep the product in its original packaging until use to maintain stability and sterility.
How is Iloprost administered?+
Iloprost is administered by intravenous or subcutaneous injection, typically as a continuous infusion using an infusion pump. The exact route, rate, and duration are prescribed by the treating physician and should be performed by trained healthcare professionals in an appropriate clinical setting.
What are the most serious risks associated with Iloprost?+
Serious adverse events include severe hypotension, pulmonary edema, significant bleeding, thrombocytopenia, and chest pain. Patients should be monitored closely for abrupt drops in blood pressure, respiratory distress, or signs of bleeding, and any such events require immediate medical attention.
Who should not use Iloprost?+
Iloprost is contraindicated in patients with known hypersensitivity to iloprost or any component of the formulation. It should also be avoided in individuals with uncontrolled severe hypotension, active bleeding disorders, or recent major surgery unless the prescriber determines that benefits outweigh the risks.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Iloprost
Route
Intravenous Use , Subcutaneous Use
Manufacturer
Teva B.V
Origin
EU

Related products

A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU
A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU
A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU
A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU