Ilgem

Ketoconazole, the active ingredient in Ilgem, is a azole antifungal presented as a topical formulation for skin use. It treats fungal skin infections such as tinea and seborrheic dermatitis in patients requiring topical therapy.

GNH USA supplies Ilgem as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketoconazole acts on dermatophyte and yeast infections of the skin and scalp.

Tinea corporis: reduces fungal growth and clears body ringworm lesions. Tinea cruris: alleviates itching and clears groin fungal infection. Tinea pedis: treats athlete's foot by eliminating dermatophytes. Seborrheic dermatitis: controls Malassezia overgrowth and improves scalp scaling. Cutaneous candidiasis: eradicates Candida species from affected skin areas.

Ketoconazole may cause local skin reactions when applied topically.

Common Side Effects: - Burning sensation at the application site. - Itching or pruritus. - Redness or erythema. - Dryness or flaking of the skin. - Stinging or mild pain. - Contact dermatitis.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis). - Extensive skin blistering or Stevens‑Johnson syndrome. - Widespread dermatitis. - Systemic absorption leading to liver enzyme abnormalities (rare). - Phototoxic reactions. - Persistent ulceration of the treated area.

When using topical ketoconazole, consider the following safety measures.

Avoid use on broken or inflamed skin: may increase systemic absorption. Do not apply near eyes or mucous membranes: can cause irritation. Limit duration to the prescribed period: prolonged use may increase irritation risk. Discontinue if severe redness, swelling, or pain develops: seek medical advice. Store at room temperature: keep in the original container, protect from moisture and light.

Ketoconazole can interact with other medicines, especially when systemic absorption occurs.

Major Interactions (Avoid): - Concurrent use of systemic azole antifungals: may increase overall azole exposure. - Warfarin: potential enhancement of anticoagulant effect. - CYP3A4 substrate drugs: risk of elevated plasma levels.

Moderate Interactions (Monitor Closely): - Topical corticosteroids: may mask irritation signs. - Hair dyes containing para‑phenylenediamine: increased risk of contact dermatitis. - Other topical antifungals: additive irritation potential.