GNH USA

Europe — EMA

Ifenec

GNH USA supplies Ifenec (Econazole Nitrate), an imidazole antifungal for tinea corporis, tinea cruris, tinea pedis and candidiasis.

Econazole Nitrate

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What is Econazole Nitrate?

Econazole nitrate, the active ingredient in Ifenec, is an imidazole antifungal presented as a topical formulation for skin use. It treats fungal infections such as athlete's foot, ringworm and candidiasis in adult and pediatric patients. GNH USA supplies Ifenec as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Econazole Nitrate used for?

Ifenec is an imidazole antifungal used to manage superficial fungal infections of the skin and mucous membranes. - Tinea corporis: reduces erythema, scaling and itching caused by ringworm of the body. - Tinea cruris: alleviates inflammation and lesions in the groin area caused by fungal infection. - Tinea pedis: clears foot skin infection, decreasing scaling, redness and discomfort. - Candidiasis: treats cutaneous candidal infections, relieving erythema and maceration.

What are the side effects of Econazole Nitrate?

Topical application of Ifenec may be associated with local skin reactions.

Common Side Effects: - Burning sensation: transient warmth at the application site. - Itching: mild pruritus following use. - Redness: localized erythema. - Dryness: skin may feel less moist. - Peeling: mild desquamation of treated skin.

Serious or Rare Side Effects: - Severe allergic reaction: swelling, hives or difficulty breathing. - Contact dermatitis: intense rash or blistering. - Skin ulceration: breakdown of epidermis. - Secondary bacterial infection: pus or increased pain at the site.

What precautions apply to Econazole Nitrate?

Before using Ifenec, consider the following safety measures. - Allergic history: avoid if known hypersensitivity to econazole or other imidazoles. - Open wounds: do not apply on extensive broken skin or severe abrasions. - Pediatric use: consult a healthcare professional before treating children. - Concomitant skin products: avoid using other topical agents on the same area unless directed. - Store at ambient temperature: keep below 25 °C, in the original container, protected from moisture and direct sunlight.

What does Econazole Nitrate interact with?

Econazole nitrate may interact with other topical agents or systemic drugs that affect skin integrity.

Major Interactions (Avoid): - Corticosteroid creams: may reduce antifungal efficacy. - Occlusive dressings: increase systemic absorption, raising risk of toxicity. - Systemic azole antifungals: potential additive inhibition of cytochrome P450 enzymes.

Moderate Interactions (Monitor Closely): - Antiseptic solutions: may cause irritation when combined. - Herbal skin preparations: monitor for unexpected skin reactions.

Frequently asked questions

What conditions is Ifenec used to treat?+
Ifenec is a topical antifungal medication indicated for the treatment of superficial fungal infections such as tinea corporis (ringworm of the body), tinea cruris (jock itch), tinea pedis (athlete’s foot) and cutaneous candidiasis. It helps relieve symptoms like redness, scaling, itching and discomfort associated with these infections.
How does econazole nitrate work in Ifenec?+
Econazole nitrate, the active ingredient in Ifenec, blocks the fungal enzyme lanosterol 14α‑demethylase, which is essential for ergosterol synthesis. By disrupting ergosterol production, the drug compromises the integrity of the fungal cell membrane, inhibiting growth and leading to the death of susceptible dermatophytes and yeasts.
What is the usual dose of Ifenec?+
The dosage of Ifenec is determined by the prescribing healthcare professional based on the type and severity of the infection, the patient’s age, and the area of skin involved. Patients should follow the specific instructions provided by their prescriber and the product label.
Is Ifenec safe to use during pregnancy or breastfeeding?+
Safety data for econazole nitrate in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any potential risk to the fetus or infant. Pregnant or nursing individuals should discuss use with their healthcare provider before starting treatment.
How do I order Ifenec from GNH USA?+
To order Ifenec, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.
How does Ifenec compare with other antifungal agents?+
Ifenec (econazole nitrate) belongs to the imidazole class, offering broad‑spectrum activity against dermatophytes and yeasts. Compared with allylamine agents such as terbinafine, econazole may have a slightly slower onset but is effective for a wide range of superficial infections. Choice of therapy depends on infection type, patient tolerance and local resistance patterns.
What are the recommended storage conditions for Ifenec?+
Ifenec should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, direct sunlight and extreme heat. Do not freeze the preparation, and ensure the container is tightly closed when not in use.
How is Ifenec applied?+
Ifenec is applied topically to the affected skin area. The prescribed amount is spread thinly over the lesion and a small margin of surrounding healthy skin, usually twice daily or as directed by a healthcare professional. Hands should be washed before and after application, and the treated area should be allowed to dry.
What are the most serious risks associated with Ifenec?+
Serious adverse reactions are rare but may include severe allergic responses such as swelling, hives, difficulty breathing, or contact dermatitis with intense rash or blistering. If any of these symptoms occur, discontinue use immediately and seek medical attention.
Who should not use Ifenec?+
Individuals with a known hypersensitivity to econazole nitrate, other imidazole antifungals, or any component of the formulation should avoid using Ifenec. It should also be avoided on extensive broken skin, deep wounds, or in patients where a systemic antifungal is required without medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Econazole Nitrate
Route
Cutaneous Use
Manufacturer
Italfarmaco S.P.A
Origin
EU

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