GNH USA

Europe — EMA

Idrolax

GNH USA supplies Idrolax (Macrogol 4000), an osmotic laxative for constipation. Request a quote for global supply. Our product meets EU quality standards.

Macrogol 4000

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What is Macrogol 4000?

Macrogol 4000, the active ingredient in Idrolax, is an osmotic laxative presented as an oral formulation for oral use. It is used to relieve constipation by softening stool and facilitating bowel movements in adults and children, and adolescents, as part of a comprehensive bowel‑health regimen.

GNH USA supplies Idrolax as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality assurance and regulatory compliance.

What is Macrogol 4000 used for?

Idrolax, an osmotic laxative, works on the gastrointestinal tract to alleviate constipation. - Constipation: softens stool and increases water content to promote regular bowel movements. - Chronic constipation: supports ongoing bowel regularity when used as directed. - Opioid‑induced constipation: counteracts reduced intestinal motility by retaining water in the lumen. - Functional constipation: improves stool consistency and eases passage in patients with irregular bowel habits. - Occasional constipation: provides rapid relief of infrequent, hard stools without the need for prescription medication. - Pregnancy‑related constipation: may be used under medical supervision to alleviate bowel difficulty.

What are the side effects of Macrogol 4000?

Macrogol 4000 may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Abdominal bloating: sensation of fullness and distension in the abdomen. - Flatulence: increased intestinal gas leading to passing of wind. - Nausea: mild feeling of queasiness without vomiting. - Mild abdominal cramps: transient, low‑intensity stomach cramps.

Serious or Rare Side Effects: - Severe dehydration: excessive fluid loss that may require medical attention. - Electrolyte imbalance: abnormal blood levels of sodium or potassium, potentially serious. - Allergic reactions: rash, itching, or angioedema indicating hypersensitivity. - Severe abdominal pain or intestinal obstruction: intense pain suggesting blockage, needing urgent care.

What precautions apply to Macrogol 4000?

Before using Idrolax, consider the following precautions to ensure safe and effective use. - Pregnancy: safety has not been established; consult a healthcare professional before use. - Renal impairment: use with caution as fluid shifts may affect kidney function. - Electrolyte disorders: monitor serum electrolytes, especially with prolonged use. - Bowel obstruction: avoid if there is known intestinal blockage or severe constipation. - Pediatric use: dosage for children should be determined by a physician. - Store at ambient temperature: keep in original packaging, protect from moisture and heat.

What does Macrogol 4000 interact with?

Idrolax can interact with certain medicines, altering its efficacy or safety profile.

Major Interactions (Avoid): - Anticholinergic agents: may reduce the laxative effect by decreasing intestinal motility. - Loop diuretics: combined use can increase risk of electrolyte disturbances. - Magnesium‑containing antacids: additive osmotic activity may cause excessive diarrhea.

Moderate Interactions (Monitor Closely): - Opioid analgesics: may diminish bowel‑movement stimulation, requiring dose adjustment. - Other laxatives: concurrent use can lead to overly soft stools or diarrhea. - Oral rehydration solutions: monitor fluid balance to avoid over‑hydration.

Frequently asked questions

What is Idrolax used for?+
Idrolax is an oral osmotic laxative indicated for the relief of occasional and chronic constipation. It works by softening stool and increasing intestinal water content, helping to restore regular bowel movements in adults and children.
How does Macrogol 4000 work?+
Macrogol 4000 is a high‑molecular‑weight polymer that is poorly absorbed in the gut. It retains water in the intestinal lumen, increasing stool bulk and softness, which stimulates peristalsis and promotes the passage of stool without stimulating secretions directly.
What is the usual dose of Idrolax?+
The appropriate dose of Idrolax is determined by a qualified healthcare professional based on the patient’s age, weight, severity of constipation, and clinical response. Patients should follow the prescriber’s instructions and not exceed the recommended amount.
Is Idrolax safe during pregnancy or breastfeeding?+
Safety data for Macrogol 4000 in pregnancy and lactation are limited. It is classified as a category unknown, so pregnant or breastfeeding women should only use Idrolax after consulting their physician to weigh potential benefits against risks.
How do I order Idrolax from GNH USA?+
To order Idrolax, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does Idrolax compare with other laxatives?+
Idrolax belongs to the osmotic laxative class, which softens stool by drawing water into the intestine. This differs from stimulant laxatives that increase intestinal motility, and from bulk‑forming agents that add fiber. Osmotic agents are generally well‑tolerated and suitable for short‑term use.
How should Idrolax be stored and handled?+
Idrolax should be stored at ambient temperature, below 25 °C, in its original container. Protect it from moisture, direct sunlight and excessive heat. Keep the product out of reach of children and do not use it after the expiry date.
How is Idrolax administered?+
Idrolax is taken orally. The powder is typically dissolved in a specified volume of water or other clear fluid, mixed thoroughly, and consumed as directed by the prescriber. It should be taken with adequate fluid intake to support its osmotic action.
What are the most serious risks to watch for when using Idrolax?+
Serious risks include severe dehydration, electrolyte disturbances such as hyponatremia or hypokalemia, and rare cases of intestinal obstruction. Patients experiencing extreme thirst, dizziness, persistent vomiting, severe abdominal pain, or signs of an allergic reaction should seek medical attention promptly.
Who should not use Idrolax?+
Idrolax is contraindicated in individuals with known or suspected bowel obstruction, perforated gastrointestinal tract, severe renal impairment, or a documented hypersensitivity to macrogol or any excipients. It should also be avoided in patients with uncontrolled electrolyte imbalances unless supervised by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Macrogol 4000
Route
Oral Use
Manufacturer
Mayoly Pharma France
Origin
EU

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