Idroclorotiazide Aurobindo

Hydrochlorothiazide, the active ingredient in Idroclorotiazide Aurobindo, is a thiazide diuretic presented as an oral tablet for systemic use. It helps lower blood pressure and reduces fluid retention in patients with hypertension or edema associated with heart, liver, or kidney conditions.

GNH USA supplies Idroclorotiazide Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier, providing reliable bulk shipments to hospitals, pharmacies, and clinics across Europe, Asia, Africa and the Americas. All batches meet stringent European pharmacopeia standards and are shipped with full documentation.

Hydrochlorothiazide is used to manage conditions that involve excess fluid or elevated blood pressure.

- Hypertension: lowers systolic and diastolic blood pressure in patients with primary or secondary hypertension. - Edema associated with congestive heart failure: promotes diuresis to reduce fluid accumulation and improve symptoms. - Edema associated with hepatic cirrhosis: facilitates removal of ascitic fluid and peripheral edema. - Edema associated with renal disease: enhances urinary excretion to alleviate fluid overload.

Hydrochlorothiazide may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Electrolyte imbalance (low potassium, sodium, magnesium) - Increased urination - Dizziness or light‑headedness - Headache - Fatigue - Nausea

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis, skin rash) - Acute gout attacks - Pancreatitis - Significant drop in blood pressure (hypotension) - Kidney function impairment - Blood dyscrasias (e.g., agranulocytosis)

Before prescribing Hydrochlorothiazide, clinicians should evaluate several safety considerations.

- Renal function: assess creatinine clearance and adjust use in severe impairment - Electrolytes: monitor serum potassium and sodium regularly - Gout: use cautiously in patients with a history of gout - Diabetes: may affect glucose control, monitor blood sugar - Pregnancy and lactation: safety not established, weigh risks and benefits - Store at ambient temperature: keep in original container, protect from moisture and light

Hydrochlorothiazide can interact with several medicines, altering its efficacy or safety profile.

Major Interactions (Avoid): - Lithium: increased lithium levels leading to toxicity - NSAIDs (e.g., ibuprofen, naproxen): may reduce diuretic effect and impair renal function - ACE inhibitors or ARBs: risk of severe potassium loss

Moderate Interactions (Monitor Closely): - Antidiabetic agents: may enhance hypoglycaemic effect - Corticosteroids: may counteract diuretic action - Digoxin: increased risk of arrhythmia due to electrolyte shifts