Europe — EMA
Idilla
GNH USA supplies Idilla (Dienogest/Estradiol Valerate), a combined oral contraceptive for contraception and menstrual cycle regulation.
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What is Dienogest, Estradiol Valerate?
Dienogest/Estradiol Valerate, the active ingredient in Idilla, is a combined oral contraceptive presented as an oral tablet for oral use. It provides hormonal contraception and helps regulate the menstrual cycle in women of reproductive age.
GNH USA supplies Idilla as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Dienogest, Estradiol Valerate used for?
Idilla, a combined oral contraceptive, is used to manage hormonal contraception and menstrual cycle regulation.
- Contraception: Prevents pregnancy by inhibiting ovulation and altering cervical mucus. - Menstrual cycle regulation: Reduces irregular bleeding and stabilises cycle length. - Endometriosis‑related pain: Alleviates pain associated with endometriosis by suppressing estrogen‑driven tissue growth.
What are the side effects of Dienogest, Estradiol Valerate?
Common Side Effects: - Nausea: mild to moderate stomach upset. - Headache: tension‑type or migraine‑like pain. - Breast tenderness: temporary swelling or discomfort. - Spotting or breakthrough bleeding: irregular light bleeding. - Weight change: slight increase or decrease. - Mood changes: irritability or mild depressive symptoms.
Serious or Rare Side Effects: - Venous thromboembolism: deep‑vein thrombosis or pulmonary embolism. - Stroke or transient ischaemic attack. - Myocardial infarction: heart attack risk, especially in smokers. - Severe allergic reaction: anaphylaxis, rash, or angioedema. - Liver dysfunction: jaundice or abnormal liver enzymes. - Hyperglycaemia: elevated blood sugar in susceptible individuals.
What precautions apply to Dienogest, Estradiol Valerate?
Before prescribing Idilla, clinicians should evaluate individual risk factors and contraindications. - Pregnancy: contraindicated (Category X); do not use during pregnancy. - Smoking: avoid in women over 35 who smoke due to increased cardiovascular risk. - Cardiovascular disease: assess history of thromboembolism, stroke, or myocardial infarction. - Liver disease: use with caution in patients with hepatic impairment. - Migraine with aura: avoid because of heightened stroke risk. - Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture and direct sunlight.
What does Dienogest, Estradiol Valerate interact with?
Idilla may interact with several medicines that alter hormone metabolism or clotting pathways.
Major Interactions (Avoid): - Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine): markedly reduce contraceptive efficacy. - Anticoagulants (e.g., warfarin): may increase risk of thrombosis. - Certain antiepileptics (e.g., phenytoin): decrease hormone levels, compromising contraception.
Moderate Interactions (Monitor Closely): - Antibiotics such as tetracycline or metronidazole: possible modest reduction in effectiveness. - Herbal supplements (e.g., St. John's wort): may lower plasma hormone concentrations. - Antifungal agents (e.g., ketoconazole): can raise hormone levels, increasing side‑effect risk.
Frequently asked questions
What is Idilla used for?+
How does Dienogest/Estradiol Valerate work in Idilla?+
What is the usual dose of Idilla?+
Is Idilla safe to use during pregnancy or breastfeeding?+
How do I order Idilla from GNH USA?+
How does Idilla compare with other combined oral contraceptives?+
What are the storage requirements for Idilla?+
How is Idilla administered?+
What are the most serious risks associated with Idilla?+
Who should not use Idilla?+
Product details
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