Ibuxal Plus

Ibuprofen and Paracetamol, the active ingredients in Ibuxal Plus, are NSAID and analgesic/antipyretic presented as an oral tablet for oral use. They relieve mild to moderate pain and reduce fever in adults.

GNH USA supplies Ibuxal Plus as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuxal Plus combines ibuprofen and paracetamol to address pain and fever through anti‑inflammatory and antipyretic mechanisms.

- Mild to moderate pain: provides analgesic relief for headaches, musculoskeletal discomfort, dental pain and other everyday aches. - Fever: lowers elevated body temperature associated with infections or inflammatory conditions. - Post‑operative discomfort: helps control pain and fever after minor surgical procedures.

Ibuxal Plus may cause adverse reactions that vary in frequency and severity.

Common Side Effects: - Nausea: mild stomach upset after ingestion. - Dyspepsia: indigestion or discomfort in the upper abdomen. - Headache: transient head pain. - Dizziness: feeling light‑headed or unsteady. - Rash: mild skin irritation or redness. - Diarrhoea: loose stools.

Serious or Rare Side Effects: - Gastrointestinal bleeding: potentially life‑threatening ulceration. - Liver injury: elevated enzymes or hepatitis. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Renal impairment: reduced kidney function, especially with dehydration. - Anaphylaxis: acute allergic reaction with airway compromise. - Thrombocytopenia: low platelet count leading to bleeding.

Before using Ibuxal Plus, consider the following safety measures.

- Assess gastrointestinal risk: evaluate history of ulcers or bleeding. - Monitor renal function: avoid in severe renal impairment or dehydration. - Check for hypersensitivity: do not use if allergic to ibuprofen, paracetamol, or other NSAIDs. - Use the lowest effective dose: limit duration to the shortest period needed for symptom control. - Caution in cardiovascular disease: NSAIDs may increase blood pressure or cardiovascular events. - Store at ambient temperature: keep in the original container, protect from moisture and heat.

Ibuxal Plus can interact with other medicines; some combinations should be avoided while others require monitoring.

Major Interactions (Avoid): - Other NSAIDs or aspirin: additive gastrointestinal bleeding risk. - Anticoagulants (e.g., warfarin, direct oral anticoagulants): increased risk of serious bleeding. - Hepatotoxic agents (e.g., isoniazid, certain antitubercular drugs): heightened potential for liver injury.

Moderate Interactions (Monitor Closely): - Antihypertensive agents (ACE inhibitors, ARBs, beta‑blockers): NSAIDs may reduce blood‑pressure control. - Lithium or methotrexate: NSAIDs can raise serum levels, necessitating therapeutic monitoring.