GNH USA

Europe — EMA

Ibustrin (Indobufen)

GNH USA supplies Ibustrin (Indobufen), a platelet aggregation inhibitor for prevention of arterial thrombosis and secondary cardiovascular event protection.

Indobufen

Request sourcing

1
Pack/s

What is Indobufen?

Indobufen, the active ingredient in Ibustrin, is a platelet aggregation inhibitor presented as an oral tablet for oral use. It helps prevent arterial thrombosis and is employed in the secondary prevention of cardiovascular events such as myocardial infarction and ischemic stroke.

GNH USA supplies Ibustrin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Indobufen used for?

Ibustrin, an antiplatelet agent, is used in conditions where platelet‑driven clot formation is a major risk.

- Prevention of arterial thrombosis: reduces the formation of occlusive clots in arteries. - Secondary prevention of myocardial infarction: lowers the chance of a recurrent heart attack. - Secondary prevention of ischemic stroke: decreases the risk of another stroke caused by arterial blockage.

What are the side effects of Indobufen?

Common Side Effects: - Nausea: mild stomach upset may occur. - Dyspepsia: indigestion or upper abdominal discomfort. - Headache: transient head pain reported by some patients. - Dizziness: occasional light‑headed sensation.

Serious or Rare Side Effects: - Severe bleeding: unexpected or prolonged hemorrhage. - Thrombocytopenia: marked reduction in platelet count. - Hepatic dysfunction: abnormal liver enzyme elevations.

What precautions apply to Indobufen?

Before initiating therapy, clinicians should consider several safety measures. - Bleeding risk assessment: evaluate patient history for prior hemorrhage. - Liver function monitoring: check hepatic enzymes periodically. - Concomitant anticoagulant review: avoid combining with other strong anticoagulants unless necessary. - Renal impairment caution: adjust use in patients with reduced kidney function. - Hypersensitivity avoidance: discontinue if allergic reactions develop. - Store at ambient temperature: keep in the original pack, protect from moisture.

What does Indobufen interact with?

Indobufen may interact with several drug classes, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Warfarin: increased anticoagulant effect and bleeding risk. - Other antiplatelet agents (e.g., clopidogrel): additive platelet inhibition. - Non‑steroidal anti‑inflammatory drugs (NSAIDs): heightened gastrointestinal bleeding. - Direct oral anticoagulants (DOACs): potential for excessive anticoagulation.

Moderate Interactions (Monitor Closely): - ACE inhibitors: possible enhancement of hypotensive effects. - Diuretics: monitor blood pressure and electrolyte balance. - Antihypertensive agents: observe for additive blood‑pressure lowering.

Frequently asked questions

What is Ibustrin used for?+
Ibustrin contains indobufen, an antiplatelet drug that is prescribed to prevent arterial thrombosis and to provide secondary prevention of cardiovascular events such as heart attacks and ischemic strokes in patients at risk of clot formation.
How does indobufen work?+
Indobufen reversibly inhibits platelet cyclooxygenase‑1, which reduces the synthesis of thromboxane A2, a potent promoter of platelet aggregation. By lowering thromboxane A2 levels, the drug diminishes platelet activation and the formation of arterial clots.
What is the usual dose of Ibustrin?+
The dosage of Ibustrin is individualized by the prescribing healthcare professional based on the patient’s clinical condition, risk factors, and concomitant therapies. The prescriber determines the appropriate strength, frequency, and duration of treatment.
Is Ibustrin safe during pregnancy or breastfeeding?+
Safety data for indobufen in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.
How do I order Ibustrin from GNH USA?+
To request Ibustrin, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Ibustrin compare with other antiplatelet drugs?+
Ibustrin (indobufen) differs from aspirin and clopidogrel by providing reversible cyclooxygenase inhibition, which may result in a distinct safety profile, especially regarding gastrointestinal tolerance. Choice of antiplatelet therapy depends on patient‑specific factors, drug interactions, and physician judgment.
What are the storage and handling requirements for Ibustrin?+
Ibustrin should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing in high‑heat or humid environments.
How is Ibustrin administered?+
Ibustrin is taken orally, usually with a glass of water. The tablet should be swallowed whole and not crushed or chewed unless otherwise directed by a healthcare professional.
What are the most serious risks associated with Ibustrin?+
The most serious risks include severe or uncontrolled bleeding, thrombocytopenia (low platelet count), and hepatic dysfunction. Patients should be monitored for signs of excessive bleeding, unusual bruising, or liver‑related symptoms and seek medical attention promptly if they occur.
Who should not use Ibustrin?+
Ibustrin is contraindicated in individuals with known hypersensitivity to indobufen or any component of the formulation, active major bleeding, or severe liver disease. Caution is also advised for patients on multiple anticoagulants or with a high bleeding risk.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Indobufen
Route
Oral Use
Manufacturer
Pfizer Spol. S R.O.
Origin
EU

Related products

Ibustrin

Ibustrin

Indobufen

Pfizer Italia S.R.L.
EU
Ibustrin

Ibustrin

Indobufen

Laboratórios Pfizer Lda.
EU
Ibustrin

Ibustrin

Indobufen

Pfizer Europe Ma Eeig
EU
Indobufene Eg

Indobufene Eg

Indobufen

Eg S.P.A.
EU