GNH USA

Europe — EMA

Ibusin

GNH USA supplies Ibusin (Phenylephrine Hydrochloride / Ibuprofen), a NSAID and decongestant for nasal congestion, headache and fever.

Phenylephrine Hydrochloride, Ibuprofen

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What is Phenylephrine Hydrochloride, Ibuprofen?

Phenylephrine Hydrochloride and Ibuprofen, the active ingredients in Ibusin, are a nonsteroidal anti-inflammatory drug (NSAID) and an alpha‑adrenergic agonist presented as an oral tablet for oral use. They relieve pain, reduce fever, and alleviate nasal congestion in adults and children when appropriate, and are commonly used for short‑term relief of these symptoms.

GNH USA supplies Ibusin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution.

What is Phenylephrine Hydrochloride, Ibuprofen used for?

Ibusin combines ibuprofen and phenylephrine to target pain, inflammation and nasal congestion pathways.

Nasal congestion: reduces swelling of nasal mucosa, improving airflow. Headache: alleviates pain through anti‑inflammatory action. Fever: lowers elevated body temperature by inhibiting prostaglandin synthesis. Minor aches and pains: provides relief from musculoskeletal discomfort.

What are the side effects of Phenylephrine Hydrochloride, Ibuprofen?

Ibusin may cause a range of adverse reactions, which are generally categorized by frequency.

Common Side Effects: - Nausea or upset stomach. - Dizziness or light‑headedness. - Dry mouth or throat irritation. - Mild headache. - Insomnia or restlessness.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulcer formation. - Severe allergic reactions such as rash, swelling or anaphylaxis. - Acute kidney injury, especially with prolonged use. - Cardiovascular events including hypertension or heart attack. - Rare skin disorders like Stevens‑Johnson syndrome.

What precautions apply to Phenylephrine Hydrochloride, Ibuprofen?

Before using Ibusin, consider the following safety measures.

Do not exceed recommended duration: limit use to the shortest time needed for symptom control. Avoid use in patients with known hypersensitivity to ibuprofen or phenylephrine. Consult a healthcare professional before use in individuals with cardiovascular disease, hypertension, or renal impairment. Use caution in pregnant or breastfeeding women; seek medical advice. Store at ambient temperature below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

What does Phenylephrine Hydrochloride, Ibuprofen interact with?

Ibusin can interact with other medicines; awareness of the interaction level helps manage risk.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin) – increased bleeding risk. - Other NSAIDs or aspirin – additive gastrointestinal toxicity. - Monoamine oxidase inhibitors (MAOIs) – heightened hypertensive response to phenylephrine.

Moderate Interactions (Monitor Closely): - Antihypertensive agents (beta‑blockers, ACE inhibitors) – possible reduction in blood‑pressure‑lowering effect. - Diuretics – may enhance renal effects of ibuprofen. - Lithium – ibuprofen can raise lithium serum levels. - Selective serotonin reuptake inhibitors (SSRIs) – modest increase in bleeding tendency.

Frequently asked questions

What is Ibusin used for?+
Ibusin is an over‑the‑counter oral medication that combines ibuprofen and phenylephrine to relieve nasal congestion, reduce fever, alleviate headache and treat minor aches and pains. It is intended for short‑term symptomatic relief in adults and children when appropriate.
How does phenylephrine hydrochloride work?+
Phenylephrine hydrochloride acts as a selective α1‑adrenergic receptor agonist. By stimulating these receptors on the blood vessels of the nasal mucosa, it causes vasoconstriction, which reduces swelling and improves airflow, providing rapid decongestion of the nasal passages.
What is the usual dose of Ibusin?+
The specific dose and dosing schedule of Ibusin are determined by a qualified prescriber based on the individual’s age, weight, medical condition and the severity of symptoms. Patients should follow the healthcare professional’s instructions and the product labeling.
Is Ibusin safe to use during pregnancy or breastfeeding?+
Safety data for Ibusin in pregnancy and lactation are limited. Ibuprofen may affect fetal renal function and phenylephrine can influence uterine blood flow. Women who are pregnant, planning pregnancy, or breastfeeding should consult their healthcare provider before using Ibusin.
How do I order Ibusin from GNH USA?+
To order Ibusin, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Ibusin compare with other NSAID‑decongestant combinations?+
Ibusin pairs ibuprofen, a well‑established NSAID, with phenylephrine, a common nasal decongestant. Compared with alternatives that use acetaminophen or pseudoephedrine, ibuprofen offers stronger anti‑inflammatory and analgesic effects, while phenylephrine provides rapid nasal vasoconstriction. The choice depends on individual tolerance, comorbidities and physician recommendation.
How should I store Ibusin?+
Store Ibusin at ambient temperature below 25 °C. Keep the tablets in their original container, protect them from moisture, excessive heat and direct sunlight. Do not store in the bathroom or near a kitchen sink where humidity is high.
How is Ibusin administered?+
Ibusin is taken orally with a glass of water. It can be taken with or without food, although taking it with food may reduce stomach irritation. Swallow the tablet whole; do not crush, chew or split unless directed by a healthcare professional.
What are the most serious risks associated with Ibusin?+
Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, acute kidney injury, and cardiovascular events like hypertension or heart attack, especially in patients with pre‑existing conditions. Prompt medical attention is required if any of these symptoms occur.
Who should not use Ibusin?+
Ibusin should be avoided by individuals with known hypersensitivity to ibuprofen, phenylephrine or any component of the formulation, as well as those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, severe renal impairment, or who are taking MAO inhibitors. Consultation with a healthcare provider is essential before use.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Phenylephrine Hydrochloride, Ibuprofen
Route
Oral Use
Manufacturer
Us Pharmacia Sp. Z O.O.
Origin
EU

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