GNH USA

Europe — EMA

Ibusal

GNH USA supplies Ibusal (Ibuprofen), a non‑steroidal anti‑inflammatory drug for pain, fever and inflammation. Request a quote for global supply today.

Ibuprofen

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What is Ibuprofen?

Ibuprofen, the active ingredient in Ibusal, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is used to relieve mild to moderate pain, reduce fever, and diminish inflammation in adults, children and adolescents.

GNH USA supplies Ibusal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Our network ensures timely delivery and regulatory compliance across diverse markets.

What is Ibuprofen used for?

Ibuprofen acts systemically to reduce inflammation and pain by inhibiting cyclo‑oxygenase enzymes, making it useful for several common conditions.

- Headache: relief of mild to moderate tension‑type or migraine‑associated pain. - Dental pain: reduction of postoperative or acute dental discomfort. - Musculoskeletal pain: alleviation of strains, sprains and low‑back aches. - Fever: lowering of elevated body temperature in infections or inflammatory states. - Arthritis: mitigation of joint inflammation and stiffness in osteoarthritis and rheumatoid arthritis.

What are the side effects of Ibuprofen?

Like all NSAIDs, ibuprofen may cause unwanted reactions ranging from mild to severe.

Common Side Effects: - Stomach upset: dyspepsia or mild abdominal discomfort. - Nausea: feeling of queasiness, sometimes with vomiting. - Dizziness: transient light‑headedness or vertigo.

Serious or Rare Side Effects: - Gastrointestinal bleeding: occult or overt bleeding, potentially leading to anemia. - Kidney injury: acute renal impairment, especially in dehydrated patients. - Severe allergic reaction: anaphylaxis or angioedema requiring immediate medical attention.

What precautions apply to Ibuprofen?

Before using Ibusal, consider the following safety measures.

- Assess gastrointestinal risk: evaluate history of ulcers or bleeding before initiating therapy. - Use lowest effective dose: limit duration and dose to the minimum needed for symptom control. - Avoid in known hypersensitivity: discontinue if rash, wheeze or swelling occurs. - Monitor renal function: check kidney parameters in patients with pre‑existing renal disease or dehydration. - Store at ambient temperature: keep below 25 °C in the original container, protect from moisture and light.

What does Ibuprofen interact with?

Ibuprofen can interact with several medicines; some require avoidance while others need close monitoring.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - ACE inhibitors (e.g., enalapril): potential reduction of antihypertensive effect and renal impairment.

Moderate Interactions (Monitor Closely): - Diuretics (e.g., furosemide): possible decrease in diuretic efficacy. - Lithium: ibuprofen may raise lithium serum concentrations. - Methotrexate: increased risk of methotrexate toxicity, especially at high doses.

Frequently asked questions

What is Ibusal used for?+
Ibusal contains ibuprofen, an over‑the‑counter NSAID used to relieve mild‑to‑moderate pain such as headache, dental pain and musculoskeletal aches, to lower fever, and to reduce inflammation in conditions like arthritis. It is intended for short‑term use in adults and children as directed by a healthcare professional.
How does ibuprofen work?+
Ibuprofen non‑selectively inhibits the cyclo‑oxygenase enzymes COX‑1 and COX‑2, which are required for the conversion of arachidonic acid to prostaglandins. By lowering prostaglandin production, it reduces the sensitisation of nerve endings to pain, diminishes fever‑inducing signals in the hypothalamus, and limits inflammation in affected tissues.
What is the usual dose of Ibusal?+
The appropriate dose of Ibusal is determined by the prescribing clinician based on the patient’s age, weight, the severity of symptoms, and any relevant medical conditions. Dosage recommendations follow national guidelines for ibuprofen, and patients should follow the prescriber’s instructions and the product label.
Is Ibusal safe during pregnancy or breastfeeding?+
Safety of ibuprofen in pregnancy and lactation depends on the trimester and individual risk factors. Generally, ibuprofen is avoided in the third trimester because of possible fetal complications, and caution is advised during the first two trimesters. Breastfeeding mothers should consult a healthcare professional before use.
How do I order Ibusal from GNH USA?+
To request Ibusal, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Ibusal compare with other NSAIDs?+
Ibusal (ibuprofen) shares the core anti‑inflammatory and analgesic mechanisms of other non‑steroidal anti‑inflammatory drugs such as naproxen or diclofenac, but it has a relatively short half‑life and a well‑established safety profile at recommended doses. Choice of NSAID often depends on individual tolerability, dosing frequency and specific clinical considerations.
How should I store Ibusal?+
Ibusal should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and do not use it after the expiry date printed on the label.
How is Ibusal administered?+
Ibusal is taken orally, usually with a full glass of water. It may be taken with or without food; however, taking it with food or milk can help minimise gastrointestinal discomfort. The tablet should be swallowed whole and not chewed or crushed unless directed by a healthcare professional.
What are the most serious risks associated with Ibusal?+
The most serious adverse events linked to ibuprofen include gastrointestinal bleeding or ulceration, acute kidney injury, and severe hypersensitivity reactions such as anaphylaxis. Patients with a history of ulcer disease, renal impairment, or known NSAID allergy should be monitored closely or avoid use.
Who should not use Ibusal?+
Ibusal should be avoided by individuals with a documented hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, patients with severe renal or hepatic impairment, and anyone who has experienced a serious cardiovascular event while using NSAIDs. Consultation with a healthcare provider is essential before starting therapy.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ibuprofen
Route
Oral Use
Manufacturer
Orion Corporation
Origin
EU

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