GNH USA

Europe — EMA

Ibuprofeno Kabi

GNH USA supplies Ibuprofeno Kabi (Ibuprofen), a nonsteroidal anti‑inflammatory drug for pain, fever and inflammation. Request a quote for global supply today.

Ibuprofen

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What is Ibuprofen?

Ibuprofen, the active ingredient in Ibuprofeno Kabi, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as an intravenous formulation for injection use. It is employed to relieve pain, reduce fever, and diminish inflammation in adult patients requiring rapid therapeutic effect, such as after surgery or with acute musculoskeletal conditions. It is indicated for short‑term management of moderate to severe pain where oral administration is not feasible.

GNH USA supplies Ibuprofeno Kabi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, clinics and procurement teams worldwide, with a focus on quality assurance and regulatory compliance.

What is Ibuprofen used for?

Ibuprofeno Kabi, an intravenous NSAID, acts on inflammatory pathways to provide analgesic, antipyretic, and anti‑inflammatory effects.

- Pain: Provides rapid relief of moderate to severe acute pain, especially postoperative or trauma‑related discomfort. - Fever: Reduces elevated body temperature by inhibiting prostaglandin synthesis in the hypothalamus. - Inflammation: Decreases swelling and tissue inflammation in musculoskeletal conditions. - Post‑operative pain: Offers short‑term control of pain after surgical procedures when oral intake is limited. - Musculoskeletal pain: Alleviates pain associated with strains, sprains, and arthritis flares.

What are the side effects of Ibuprofen?

Adverse reactions to Ibuprofeno Kabi can vary in frequency and severity.

Common Side Effects: - Nausea: mild to moderate feeling of sickness. - Headache: transient headache during treatment. - Dizziness: occasional light‑headedness. - Injection site pain: discomfort at the infusion site.

Serious or Rare Side Effects: - Gastrointestinal bleeding: severe bleeding in the stomach or intestines. - Renal impairment: acute kidney injury or reduced renal function. - Severe hypersensitivity: anaphylaxis, skin rash, or angio‑edema.

What precautions apply to Ibuprofen?

Before initiating therapy, clinicians should evaluate patient‑specific risk factors and monitor for potential complications. - Renal function: assess baseline renal status and monitor during therapy. - Bleeding risk: avoid in patients with active gastrointestinal ulcer or coagulopathy. - Cardiovascular health: use cautiously in patients with hypertension or heart failure. - Pregnancy: consider risk/benefit; generally avoid in the third trimester. - Drug interactions: review concomitant NSAIDs, anticoagulants, and ACE inhibitors. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

What does Ibuprofen interact with?

Ibuprofeno Kabi may interact with several drug classes; careful review is essential.

Major Interactions (Avoid): - Other NSAIDs: increased risk of gastrointestinal bleeding. - Anticoagulants (e.g., warfarin): heightened bleeding risk. - ACE inhibitors or ARBs: may impair renal function.

Moderate Interactions (Monitor Closely): - Diuretics: monitor renal function and electrolytes. - SSRIs or SNRIs: observe for signs of bleeding.

Frequently asked questions

What is Ibuprofeno Kabi used for?+
Ibuprofeno Kabi is an intravenous formulation of ibuprofen used in hospital settings to treat moderate to severe acute pain, reduce fever, and control inflammation. It is commonly employed after surgery, for musculoskeletal injuries, and in other situations where rapid symptom relief is needed and oral administration is not feasible.
How does ibuprofen work?+
Ibuprofen inhibits the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin production, ibuprofen reduces the sensitization of pain receptors, lowers the hypothalamic set‑point for temperature, and dampens the inflammatory response, providing analgesic, antipyretic, and anti‑inflammatory effects.
What is the usual dose of Ibuprofeno Kabi?+
The appropriate dose of Ibuprofeno Kabi is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and renal function. Healthcare professionals calculate the infusion rate and total daily amount according to established hospital protocols and the product’s labeling.
Is Ibuprofeno Kabi safe during pregnancy or breastfeeding?+
Safety of ibuprofen during pregnancy and lactation depends on the trimester and clinical context. Generally, ibuprofen is avoided in the third trimester because of potential fetal cardiovascular effects. During the first and second trimesters, the prescriber must weigh benefits against risks. Ibuprofen does pass into breast milk in small amounts, so a risk‑benefit assessment is required before use while breastfeeding.
How do I order Ibuprofeno Kabi from GNH USA?+
To order Ibuprofeno Kabi, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifying trade or institutional credentials before providing pricing, availability, shipping details (including cold‑chain handling if needed), and necessary import documentation.
How does Ibuprofeno Kabi compare with other NSAIDs?+
Ibuprofeno Kabi offers the same pharmacologic profile as other ibuprofen products but in an intravenous form, allowing rapid onset and use when oral intake is impossible. Compared with stronger injectable NSAIDs such as ketorolac, ibuprofen generally has a lower risk of gastrointestinal ulceration and renal toxicity, though dosing limits and monitoring requirements remain similar.
How should Ibuprofeno Kabi be stored and handled?+
Ibuprofeno Kabi must be stored at 2‑8 °C in a refrigerator, protected from light, and must not be frozen or shaken. Before administration, the vial should be inspected for particulate matter and used within the time frame indicated on the label after removal from refrigeration.
How is Ibuprofeno Kabi given or administered?+
Ibuprofeno Kabi is administered by intravenous infusion. The prescribing clinician determines the infusion rate and total dose, which is typically diluted in an appropriate carrier solution and infused over a specified period, often 15‑30 minutes, according to hospital protocols and the patient’s clinical status.
What are the most serious risks to watch for with Ibuprofeno Kabi?+
Serious risks include gastrointestinal bleeding, acute renal impairment, severe hypersensitivity reactions such as anaphylaxis, and cardiovascular events like myocardial infarction or stroke, especially in patients with existing cardiovascular disease. Prompt recognition of symptoms such as severe abdominal pain, sudden drop in urine output, rash, or chest discomfort is essential.
Who should not use Ibuprofeno Kabi?+
Ibuprofeno Kabi should be avoided in patients with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulceration or bleeding, severe uncontrolled hypertension, advanced heart failure, and in the third trimester of pregnancy. Caution is also advised for patients with impaired renal or hepatic function, and those taking anticoagulants or other NSAIDs.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ibuprofen
Route
Intravenous Use
Manufacturer
Fresenius Kabi España S.A.U.
Origin
EU

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