Europe — EMA
Ibuprofeno/Fenilefrina Nutra Essential (Phenylephrine Hydrochloride, Ibuprofen)
GNH USA supplies Ibuprofeno/Fenilefrina Nutra Essential (Ibuprofen / Phenylephrine), a NSAID and nasal decongestant for pain, fever and congestion.
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What is Phenylephrine Hydrochloride, Ibuprofen?
Ibuprofen, the active ingredient in Ibuprofeno/Fenilefrina Nutra Essential, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It provides relief of mild to moderate pain, reduces fever, and is combined with phenylephrine to alleviate nasal congestion associated with colds or sinusitis in adults and children, and can be used as needed for symptomatic relief.
GNH USA supplies Ibuprofeno/Fenilefrina Nutra Essential as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on reliable quality and regulatory compliance.
What is Phenylephrine Hydrochloride, Ibuprofen used for?
Ibuprofen/Phenylephrine is indicated for conditions involving pain, fever, and nasal congestion related to upper respiratory infections.
- Mild to moderate pain: provides analgesic effect by reducing inflammation and pain perception. - Fever: lowers elevated body temperature through prostaglandin inhibition. - Nasal congestion due to common cold or sinusitis: relieves blockage by vasoconstriction of nasal mucosa.
What are the side effects of Phenylephrine Hydrochloride, Ibuprofen?
Common Side Effects: - Dyspepsia or stomach upset. - Nausea or vomiting. - Headache. - Dizziness. - Increased blood pressure. - Nasal dryness or irritation.
Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration. - Severe allergic reactions such as anaphylaxis. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Acute renal impairment. - Cardiovascular events including myocardial infarction. - Severe hypertension or hypertensive crisis.
What precautions apply to Phenylephrine Hydrochloride, Ibuprofen?
Before using this product, consider the following precautions: - Assess gastrointestinal risk: evaluate history of ulcers or bleeding before initiating therapy. - Avoid in known hypersensitivity: do not use if allergic to ibuprofen, phenylephrine, or any excipients. - Monitor blood pressure: phenylephrine may raise systolic and diastolic values. - Use with caution in renal or hepatic impairment: dose adjustment or medical supervision may be required. - Avoid concomitant use with other NSAIDs or anticoagulants: increased risk of bleeding. - Store at ambient temperature: keep in the original container, protect from moisture and heat.
What does Phenylephrine Hydrochloride, Ibuprofen interact with?
Ibuprofeno/Fenilefrina Nutra Essential may interact with several medicines.
Major Interactions (Avoid): - Other NSAIDs: additive risk of gastrointestinal bleeding. - Anticoagulants (e.g., warfarin, DOACs): heightened bleeding tendency. - Monoamine oxidase inhibitors or tricyclic antidepressants: may potentiate phenylephrine‑induced hypertension. - MAO inhibitors: risk of severe hypertensive response.
Moderate Interactions (Monitor Closely): - Beta‑blockers: may diminish decongestant effectiveness. - Antihypertensive agents or diuretics: monitor blood pressure for additive effects. - Lithium: NSAIDs can increase serum lithium concentrations, requiring level checks.



