GNH USA

Europe — EMA

Ibuprofeno/Fenilefrina Nutra Essential

GNH USA supplies Ibuprofeno/Fenilefrina Nutra Essential (Ibuprofen / Phenylephrine), a NSAID and nasal decongestant for pain, fever and congestion.

Phenylephrine Hydrochloride, Ibuprofen

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What is Phenylephrine Hydrochloride, Ibuprofen?

Ibuprofen, the active ingredient in Ibuprofeno/Fenilefrina Nutra Essential, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It provides relief of mild to moderate pain, reduces fever, and is combined with phenylephrine to alleviate nasal congestion associated with colds or sinusitis in adults and children, and can be used as needed for symptomatic relief.

GNH USA supplies Ibuprofeno/Fenilefrina Nutra Essential as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on reliable quality and regulatory compliance.

What is Phenylephrine Hydrochloride, Ibuprofen used for?

Ibuprofen/Phenylephrine is indicated for conditions involving pain, fever, and nasal congestion related to upper respiratory infections.

- Mild to moderate pain: provides analgesic effect by reducing inflammation and pain perception. - Fever: lowers elevated body temperature through prostaglandin inhibition. - Nasal congestion due to common cold or sinusitis: relieves blockage by vasoconstriction of nasal mucosa.

What are the side effects of Phenylephrine Hydrochloride, Ibuprofen?

Common Side Effects: - Dyspepsia or stomach upset. - Nausea or vomiting. - Headache. - Dizziness. - Increased blood pressure. - Nasal dryness or irritation.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration. - Severe allergic reactions such as anaphylaxis. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Acute renal impairment. - Cardiovascular events including myocardial infarction. - Severe hypertension or hypertensive crisis.

What precautions apply to Phenylephrine Hydrochloride, Ibuprofen?

Before using this product, consider the following precautions: - Assess gastrointestinal risk: evaluate history of ulcers or bleeding before initiating therapy. - Avoid in known hypersensitivity: do not use if allergic to ibuprofen, phenylephrine, or any excipients. - Monitor blood pressure: phenylephrine may raise systolic and diastolic values. - Use with caution in renal or hepatic impairment: dose adjustment or medical supervision may be required. - Avoid concomitant use with other NSAIDs or anticoagulants: increased risk of bleeding. - Store at ambient temperature: keep in the original container, protect from moisture and heat.

What does Phenylephrine Hydrochloride, Ibuprofen interact with?

Ibuprofeno/Fenilefrina Nutra Essential may interact with several medicines.

Major Interactions (Avoid): - Other NSAIDs: additive risk of gastrointestinal bleeding. - Anticoagulants (e.g., warfarin, DOACs): heightened bleeding tendency. - Monoamine oxidase inhibitors or tricyclic antidepressants: may potentiate phenylephrine‑induced hypertension. - MAO inhibitors: risk of severe hypertensive response.

Moderate Interactions (Monitor Closely): - Beta‑blockers: may diminish decongestant effectiveness. - Antihypertensive agents or diuretics: monitor blood pressure for additive effects. - Lithium: NSAIDs can increase serum lithium concentrations, requiring level checks.

Frequently asked questions

What is Ibuprofeno/Fenilefrina Nutra Essential used for?+
Ibuprofeno/Fenilefrina Nutra Essential is an over‑the‑counter oral tablet that combines ibuprofen, an NSAID, with phenylephrine, a nasal decongestant. It is used to relieve mild to moderate pain, reduce fever, and alleviate nasal congestion caused by the common cold or sinusitis. The combination targets both systemic symptoms and upper‑respiratory tract blockage.
How do the active ingredients work?+
Ibuprofen works by inhibiting cyclooxygenase enzymes, which reduces the production of prostaglandins that mediate pain, inflammation, and fever. Phenylephrine acts as an alpha‑1 adrenergic agonist, causing blood vessels in the nasal mucosa to constrict, which decreases swelling and opens the nasal passages. Together they provide analgesic, antipyretic, and decongestant effects.
What is the usual dose of this medication?+
The appropriate dose of Ibuprofeno/Fenilefrina Nutra Essential is determined by a qualified healthcare professional based on the patient’s age, weight, medical condition, and other medications. The prescribing information on the product label provides detailed dosing guidance, and patients should follow the prescriber’s instructions without exceeding the recommended amount.
Is Ibuprofeno/Fenilefrina Nutra Essential safe during pregnancy or breastfeeding?+
Safety data for the combined use of ibuprofen and phenylephrine in pregnancy and lactation are limited. Ibuprofen is generally avoided in the third trimester, and phenylephrine may affect uterine blood flow. Women who are pregnant, planning pregnancy, or breastfeeding should consult their physician before using this product to weigh potential risks and benefits.
How do I order Ibuprofeno/Fenilefrina Nutra Essential from GNH USA?+
To place an order, visit the product page on gnh-usa.com and submit an enquiry with the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, requesting verification of trade or institutional credentials. The sales team will then respond with pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.
How does this product compare with other common cold remedies?+
Compared with a typical paracetamol‑pseudoephedrine combination, Ibuprofeno/Fenilefrina Nutra Essential offers NSAID‑based pain and fever relief rather than acetaminophen, which may be preferable for patients needing anti‑inflammatory action. Phenylephrine provides decongestant activity similar to pseudoephedrine but has a different safety profile, especially regarding cardiovascular effects and drug‑interaction potential.
What are the storage and handling requirements?+
Store the tablets at ambient temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and direct sunlight. Do not store in bathrooms or near heat sources. Ensure the container is tightly closed after each use to maintain product stability.
How is Ibuprofeno/Fenilefrina Nutra Essential administered?+
The medication is taken orally with a full glass of water. It can be taken with or without food, although taking it with food may reduce stomach irritation. Swallow the tablet whole; do not crush or chew unless specifically instructed by a healthcare professional.
What are the most serious risks associated with this medication?+
Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment, and cardiovascular events like myocardial infarction. Phenylephrine can cause hypertensive crises, especially in patients with pre‑existing hypertension or when combined with certain antidepressants. Patients should seek immediate medical attention if they experience severe stomach pain, blood in stool, rash, swelling, or sudden high blood pressure.
Who should not use Ibuprofeno/Fenilefrina Nutra Essential?+
Individuals with known hypersensitivity to ibuprofen, phenylephrine, or any excipients should avoid the product. It is also contraindicated in patients with active gastrointestinal ulcers, severe renal or hepatic disease, uncontrolled hypertension, or those taking monoamine oxidase inhibitors. Pregnant women in the third trimester and breastfeeding mothers should consult a physician before use.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Phenylephrine Hydrochloride, Ibuprofen
Route
Oral Use
Manufacturer
Farmalider, S.A.
Origin
EU

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