Ibuprofen/Pseudoephedrin

Ibuprofen, the active ingredient in Ibuprofen/Pseudoephedrine, is a non‑steroidal anti‑inflammatory drug presented as an oral formulation for systemic use. It provides analgesic, antipyretic and anti‑inflammatory effects and is combined with pseudoephedrine to relieve nasal congestion. GNH USA supplies Ibuprofen/Pseudoephedrine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen/Pseudoephedrine acts on pain, fever and nasal congestion pathways, offering combined relief for several common conditions.

Nasal congestion due to common cold: reduces swelling of nasal passages and improves airflow. Sinusitis‑related headache: alleviates pain and pressure associated with sinus inflammation. Fever and mild to moderate pain: lowers body temperature and eases discomfort.

Common Side Effects: - Nausea or stomach upset - Dizziness or mild headache - Insomnia or restlessness - Increased heart rate

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) - Gastrointestinal bleeding or ulceration - Marked elevation of blood pressure - Cardiac arrhythmias or palpitations - Hallucinations or severe central nervous system effects - Stevens‑Johnson syndrome or toxic epidermal necrolysis

Before using this combination product, consider the following safety measures.

Assess cardiovascular status: pseudoephedrine may raise blood pressure. Avoid use in patients with peptic ulcer disease: ibuprofen can exacerbate gastric irritation. Monitor renal function: NSAIDs may affect kidney performance. Consider drug interactions: avoid concurrent MAO inhibitors. Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

When co‑administered with other medicines, ibuprofen/pseudoephedrine may require careful management.

Major Interactions (Avoid): - MAO inhibitors: risk of hypertensive crisis with pseudoephedrine. - Anticoagulants (e.g., warfarin): increased bleeding risk with ibuprofen. - Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency. - Lithium: pseudoephedrine may raise serum lithium levels.

Moderate Interactions (Monitor Closely): - Diuretics: may reduce the antihypertensive effect of pseudoephedrine. - ACE inhibitors: possible attenuation of blood‑pressure control. - Beta‑blockers: may blunt pseudoephedrine‑induced tachycardia.