GNH USA

Europe — EMA

Ibuprofen/Phenylephrine Opella

GNH USA supplies Ibuprofen/Phenylephrine Opella (Ibuprofen), a NSAID and nasal decongestant for headache, fever, minor aches, pains and nasal congestion.

Phenylephrine Hydrochloride, Ibuprofen

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What is Phenylephrine Hydrochloride, Ibuprofen?

Ibuprofen, the active ingredient in Ibuprofen/Phenylephrine Opella, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for systemic use. It alleviates headache, fever, minor aches and pains, and, together with phenylephrine, helps reduce nasal congestion associated with colds.

GNH USA supplies Ibuprofen/Phenylephrine Opella as a licensed, GDP‑compliant international pharmaceutical supplier, adhering to EU quality standards and providing the product to hospitals, pharmacies and clinics worldwide. The company ensures consistent batch release, proper documentation, and timely delivery across multiple markets.

What is Phenylephrine Hydrochloride, Ibuprofen used for?

Ibuprofen/Phenylephrine Opella combines an NSAID with an alpha‑adrenergic decongestant to address pain‑related and nasal‑congestion conditions.

- Headache: provides analgesic relief and reduces associated nasal pressure. - Fever: lowers elevated body temperature through anti‑pyretic action. - Nasal congestion due to common cold or sinusitis: constricts nasal blood vessels to improve airflow. - Minor aches and pains: eases muscle or joint discomfort.

What are the side effects of Phenylephrine Hydrochloride, Ibuprofen?

Common Side Effects: - Nausea: mild stomach upset may occur. - Dizziness: transient light‑headedness reported. - Nasal dryness: due to vasoconstriction. - Mild headache: occasional paradoxical headache.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulcer: severe stomach pain or blood in stool. - Anaphylaxis: rapid onset of rash, swelling, and breathing difficulty. - Severe hypertension or cardiovascular events: marked rise in blood pressure or chest pain.

What precautions apply to Phenylephrine Hydrochloride, Ibuprofen?

Before using this product, consider the following precautions: - Hypersensitivity: avoid if known allergy to ibuprofen, phenylephrine, or other NSAIDs. - Peptic ulcer disease: use with caution in patients with active ulcers. - Cardiovascular risk: monitor blood pressure in patients with hypertension or heart disease. - Anticoagulant therapy: assess bleeding risk when combined with warfarin or similar agents. - Pregnancy and lactation: consult a healthcare professional before use. - Store at ambient temperature: keep in the original container, protect from moisture and heat.

What does Phenylephrine Hydrochloride, Ibuprofen interact with?

Ibuprofen/Phenylephrine Opella may interact with other medicines.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Monoamine oxidase inhibitors (MAOIs): may potentiate hypertensive effects of phenylephrine.

Moderate Interactions (Monitor Closely): - Antihypertensive agents (beta‑blockers, ACE inhibitors): phenylephrine may reduce their efficacy. - Lithium: NSAIDs can raise lithium serum levels. - Selective serotonin reuptake inhibitors (SSRIs): modestly increased bleeding risk.

Frequently asked questions

What is Ibuprofen/Phenylephrine Opella used for?+
Ibuprofen/Phenylephrine Opella is an over‑the‑counter oral combination indicated for the temporary relief of headache, fever, minor aches and pains, and for nasal congestion associated with the common cold or sinusitis.
How does ibuprofen work in this product?+
Ibuprofen blocks cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, reducing prostaglandin production, which lowers inflammation, pain, and fever. Phenylephrine stimulates alpha‑1 receptors, tightening nasal blood vessels to ease congestion.
What is the usual dose of Ibuprofen/Phenylephrine Opella?+
The appropriate dose is determined by the prescribing healthcare professional based on the patient’s age, severity of symptoms, and other medications. Patients should follow the prescriber’s instructions and the product label.
Is Ibuprofen/Phenylephrine Opella safe during pregnancy or breastfeeding?+
Safety has not been established. Ibuprofen is generally avoided in the third trimester, and phenylephrine is not recommended without medical advice. Pregnant, planning‑pregnant, or breastfeeding women should consult their healthcare provider before use.
How do I order Ibuprofen/Phenylephrine Opella from GNH USA?+
Submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does this product compare with other OTC pain‑relief options?+
Compared with single‑ingredient ibuprofen tablets, this combination adds phenylephrine to address nasal congestion, offering dual symptom relief. Unlike acetaminophen, ibuprofen provides anti‑inflammatory effects but shares similar NSAID cautions. Choice depends on whether congestion is a concurrent symptom.
How should Ibuprofen/Phenylephrine Opella be stored and handled?+
Store at ambient temperature, preferably below 25 °C, in the original packaging to protect from moisture and light. Keep the product out of reach of children and do not use after the expiry date printed on the pack.
How is Ibuprofen/Phenylephrine Opella administered?+
The medication is taken orally, usually with a full glass of water. It may be taken with or without food; taking it with food can reduce stomach irritation. Follow the dosage instructions provided by the prescriber.
What are the most serious risks associated with this product?+
Serious risks include gastrointestinal bleeding or ulcer, severe allergic reactions such as anaphylaxis, marked hypertension, and renal impairment. If symptoms like severe stomach pain, vomiting blood, rash, swelling, or breathing difficulty occur, seek medical attention immediately.
Who should not use Ibuprofen/Phenylephrine Opella?+
People with known hypersensitivity to ibuprofen, phenylephrine, or any NSAID, those with active peptic ulcer disease, uncontrolled hypertension, significant heart failure, or who are taking anticoagulants without medical supervision should avoid this product. Consultation with a healthcare professional is essential.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Phenylephrine Hydrochloride, Ibuprofen
Route
Oral Use
Manufacturer
Stada Arzneimittel Ag
Origin
EU

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