GNH USA

Europe — EMA

Ibuprofen/Phenylephrin Stada

GNH USA supplies Ibuprofen/Phenylephrin Stada (Ibuprofen/Phenylephrine), a nonsteroidal anti-inflammatory and nasal decongestant for pain, fever

Phenylephrine Hydrochloride, Ibuprofen

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What is Phenylephrine Hydrochloride, Ibuprofen?

Ibuprofen and phenylephrine hydrochloride, the active ingredients in Ibuprofen/Phenylephrin Stada, are a nonsteroidal anti‑inflammatory drug (NSAID) and an alpha‑adrenergic agonist presented as an oral tablet for oral use. It provides analgesic, antipyretic, anti‑inflammatory and nasal decongestant effects for adults experiencing mild to moderate pain, fever, headache and nasal congestion.

GNH USA supplies Ibuprofen/Phenylephrin Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Phenylephrine Hydrochloride, Ibuprofen used for?

Ibuprofen/Phenylephrin Stada combines an NSAID and a nasal decongestant to address pain, fever and congestion. - Nasal congestion: reduces swelling of nasal mucosa and eases breathing. - Headache: alleviates pain through prostaglandin inhibition. - Fever: lowers elevated body temperature via anti‑pyretic action. - Mild to moderate pain: provides relief from aches such as muscular or dental pain.

What are the side effects of Phenylephrine Hydrochloride, Ibuprofen?

Common Side Effects: - Gastrointestinal discomfort: nausea, heartburn or dyspepsia. - Dizziness or mild headache. - Nervousness or insomnia. - Mild increase in blood pressure.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulcer perforation. - Severe allergic reactions such as rash, angioedema or anaphylaxis. - Significant hypertension or cardiovascular events. - Acute renal impairment, especially in patients with pre‑existing kidney disease.

What precautions apply to Phenylephrine Hydrochloride, Ibuprofen?

Before using Ibuprofen/Phenylephrin Stada, consider the following precautions: - Gastrointestinal risk: avoid in patients with active ulcer disease or a history of GI bleeding. - Cardiovascular caution: use carefully in individuals with hypertension, heart failure or coronary artery disease. - Renal function: monitor kidney function in patients with chronic renal impairment. - Pregnancy and lactation: consult a healthcare professional before use. - Drug interactions: review concomitant medications for potential interactions. - Store at ambient temperature (below 25°C): keep in the original pack, protect from moisture.

What does Phenylephrine Hydrochloride, Ibuprofen interact with?

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Lithium: ibuprofen may raise lithium serum levels.

Moderate Interactions (Monitor Closely): - Antihypertensive agents (beta‑blockers, ACE inhibitors): phenylephrine may reduce their efficacy. - Selective serotonin reuptake inhibitors (SSRIs): may modestly increase bleeding risk.

Frequently asked questions

What is Ibuprofen/Phenylephrin Stada used for?+
Ibuprofen/Phenylephrin Stada is an over‑the‑counter oral product that combines ibuprofen, an NSAID, with phenylephrine hydrochloride, a nasal decongestant. It is indicated for the temporary relief of mild to moderate pain, fever, headache and nasal congestion associated with the common cold or sinus pressure in adults.
How does ibuprofen work in this product?+
Ibuprofen blocks the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for prostaglandin production. By reducing prostaglandins, it diminishes inflammation, lowers fever, and alleviates pain. Phenylephrine, the second component, activates α1‑adrenergic receptors in the nasal mucosa, causing blood‑vessel constriction and reducing swelling.
What is the usual dose of Ibuprofen/Phenylephrin Stada?+
The appropriate dose is determined by a qualified prescriber or according to the product label. Dosage depends on factors such as age, weight, severity of symptoms and any concurrent medical conditions. Patients should follow the specific instructions provided by their healthcare professional or the packaging.
Is Ibuprofen/Phenylephrin Stada safe during pregnancy or breastfeeding?+
Safety data for this combination in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before using the product. The prescriber will weigh potential benefits against any possible risks to the mother and infant.
How do I order Ibuprofen/Phenylephrin Stada from GNH USA?+
To place an order, visit the product page on gnh-usa.com and submit an enquiry with the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.
How does this product compare with other NSAID‑decongestant combinations?+
Ibuprofen/Phenylephrin Stada pairs ibuprofen, a widely used NSAID, with phenylephrine, a selective α1‑agonist. Compared with products that contain pseudoephedrine, phenylephrine has a shorter duration of action and a lower risk of central nervous system stimulation, but may be less effective in severe congestion. The ibuprofen component offers stronger anti‑inflammatory and analgesic effects than acetaminophen‑based combos.
What are the storage and handling requirements for Ibuprofen/Phenylephrin Stada?+
Store the tablets at ambient temperature, preferably below 25 °C, in the original container to protect them from moisture and light. Keep the product out of reach of children and do not use it after the expiry date printed on the packaging.
How is Ibuprofen/Phenylephrin Stada administered?+
The medication is taken orally with a full glass of water. It may be taken with or without food, although taking it with food can reduce the chance of stomach irritation. Swallow the tablet whole; do not crush, chew, or split it unless directed by a healthcare professional.
What are the most serious risks associated with this product?+
Serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, significant hypertension or cardiovascular events, and acute kidney injury, especially in patients with pre‑existing renal disease or who are taking interacting medications.
Who should not use Ibuprofen/Phenylephrin Stada?+
Individuals with a known hypersensitivity to ibuprofen, phenylephrine, or any other component of the formulation should avoid it. It is also contraindicated in patients with active gastrointestinal ulceration, severe uncontrolled hypertension, recent coronary artery bypass grafting, or severe renal impairment without medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Phenylephrine Hydrochloride, Ibuprofen
Route
Oral Use
Manufacturer
Stada Gmbh
Origin
EU

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