Europe — EMA
Ibuprofen Pfleger (Ibuprofen D,l-Lysinate)
GNH USA supplies Ibuprofen Pfleger (Ibuprofen), a non‑steroidal anti‑inflammatory drug for pain, fever and inflammation.
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What is Ibuprofen D,l-Lysinate?
Ibuprofen D,l-Lysinate, the active ingredient in Ibuprofen Pfleger, is a non‑steroidal anti‑inflammatory drug presented as an oral dosage form for oral use. It provides analgesic, antipyretic and anti‑inflammatory effects and is indicated for the temporary relief of mild to moderate pain, fever and inflammatory conditions in the general population.
GNH USA supplies Ibuprofen Pfleger as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide with a focus on quality assurance and regulatory compliance.
What is Ibuprofen D,l-Lysinate used for?
Ibuprofen Pfleger, an NSAID that inhibits prostaglandin synthesis, is used for several common conditions.
- Pain: Provides temporary relief of mild to moderate pain such as headache, toothache, menstrual cramps, or musculoskeletal discomfort. - Fever: Reduces elevated body temperature associated with infections or inflammatory processes. - Inflammation: Decreases swelling and inflammation in conditions like minor sprains, strains, or arthritic flare‑ups.
What are the side effects of Ibuprofen D,l-Lysinate?
Like other NSAIDs, Ibuprofen Pfleger may cause a range of adverse reactions, most of which are dose‑related and reversible.
Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or mild abdominal pain. - Headache: transient headache episodes. - Dizziness: occasional light‑headedness. - Rash: mild skin erythema or itching.
Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding: severe stomach or intestinal bleeding. - Renal impairment: reduced kidney function or acute kidney injury. - Hepatotoxicity: elevated liver enzymes or hepatitis. - Severe allergic reaction: anaphylaxis, angioedema, or bronchospasm.
What precautions apply to Ibuprofen D,l-Lysinate?
When using Ibuprofen Pfleger, consider the following precautions to minimize risk.
- Assess renal function: avoid use in patients with severe kidney disease or dehydration. - Monitor gastrointestinal risk: use with caution in individuals with a history of ulcers or bleeding. - Cardiovascular caution: limit use in patients with uncontrolled hypertension or heart failure. - Concomitant medications: review use with anticoagulants, other NSAIDs, or corticosteroids. - Pregnancy and lactation: consult a healthcare professional before use during pregnancy or breastfeeding. - Store at ambient temperature: keep below 25 °C in the original packaging, protected from moisture and direct sunlight.
What does Ibuprofen D,l-Lysinate interact with?
Ibuprofen Pfleger can interact with several medicines; awareness of major and moderate interactions helps ensure safe therapy.
Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - High‑dose aspirin: heightened gastrointestinal toxicity. - SSRIs: elevated bleeding risk.
Moderate Interactions (Monitor Closely): - Diuretics: may reduce antihypertensive effect. - Methotrexate: reduced renal clearance can increase toxicity.



