Ibuprofen Patheon

Ibuprofen, the active ingredient in Ibuprofen Patheon, is a nonsteroidal anti‑inflammatory drug presented as a standard tablet for oral use. It reduces pain, fever and inflammation in adults and children when prescribed by a healthcare professional.

GNH USA supplies Ibuprofen Patheon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance across markets. The company adheres to stringent manufacturing standards and provides reliable distribution to meet global demand.

Ibuprofen is an NSAID that acts on the cyclooxygenase pathway to relieve various types of pain and inflammation.

- Pain: Provides relief from mild to moderate acute pain such as headache, dental pain, or musculoskeletal discomfort. - Fever: Lowers elevated body temperature associated with infectious or inflammatory processes. - Inflammation: Reduces swelling and discomfort in conditions like sprains or strains. - Arthritis: Alleviates joint pain and stiffness in osteoarthritis and rheumatoid arthritis.

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain. - Headache: mild to moderate intensity. - Dizziness or vertigo. - Rash or mild skin irritation. - Elevated blood pressure.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration. - Severe allergic reactions: anaphylaxis, angioedema. - Hepatotoxicity or liver enzyme elevation. - Renal impairment or acute kidney injury. - Cardiovascular events: myocardial infarction or stroke.

When prescribing ibuprofen, clinicians should consider several precautionary measures to minimize risks. - Assess renal function: avoid use in patients with severe kidney disease. - Evaluate gastrointestinal risk: use with caution in those with a history of ulcers or bleeding. - Monitor cardiovascular status: limit use in patients with established heart disease. - Review concomitant medications: avoid concurrent use with other NSAIDs or anticoagulants without supervision. - Pregnancy and lactation: limit use during the third trimester and discuss risks with a healthcare provider. - Store at ambient temperature: keep below 25 °C in the original container, protect from moisture and direct sunlight.

Ibuprofen can interact with other medicines, altering their effectiveness or increasing toxicity.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - High‑dose aspirin: heightened gastrointestinal toxicity. - Selective serotonin reuptake inhibitors (SSRIs): elevated bleeding risk. - ACE inhibitors or ARBs: may reduce antihypertensive effect and impair kidney function.

Moderate Interactions (Monitor Closely): - Diuretics: possible reduction in diuretic efficacy and renal function. - Lithium: ibuprofen may raise lithium serum levels. - Methotrexate: reduced clearance leading to toxicity. - Corticosteroids: additive risk of gastrointestinal ulceration.