Ibuprofen/Paracetamol 1 A Pharma

Ibuprofen, the active ingredient in Ibuprofen/Paracetamol 1 A Pharma, is a NSAID/Analgesic presented as a combined oral tablet for oral use. It is used to relieve pain, reduce fever, and manage inflammation in adults and children when appropriate, treating mild to moderate pain, fever, and musculoskeletal discomfort in a broad patient population.

GNH USA supplies Ibuprofen/Paracetamol 1 A Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across global markets.

Ibuprofen/Paracetamol is used to manage pain and fever through combined anti‑inflammatory and antipyretic mechanisms.

- Pain: provides relief of mild to moderate nociceptive pain. - Fever: reduces elevated body temperature. - Headache: alleviates tension‑type and migraine‑associated headache. - Musculoskeletal pain: eases discomfort from strains, sprains and arthritic conditions.

Adverse reactions may occur with any medication. Most are mild and reversible.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia, or mild abdominal pain. - Dizziness or light‑headedness. - Headache. - Transient skin rash. - Mild elevation of liver enzymes.

Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding. - Severe skin reactions such as Stevens‑Johnson syndrome. - Hepatic injury or jaundice. - Acute renal impairment or failure. - Anaphylactic or severe allergic reactions. - Hematologic abnormalities (e.g., thrombocytopenia).

Before using Ibuprofen/Paracetamol, consider the following safety measures.

- Assess renal function: avoid in severe renal impairment. - Evaluate hepatic status: use with caution in liver disease. - Use the lowest effective dose: limit duration to reduce gastrointestinal risk. - Avoid concomitant NSAIDs: increased bleeding and ulcer risk. - Contraindicated in known hypersensitivity to ibuprofen or paracetamol. - Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Ibuprofen/Paracetamol can interact with other medicines; monitoring is advised.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened bleeding risk. - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Lithium: increased lithium serum concentrations.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: possible reduction in antihypertensive effect. - Diuretics: potential for reduced renal perfusion. - Alcohol: increased risk of liver injury and gastrointestinal irritation.