GNH USA

Europe — EMA

Ibuprofen Mae Holding Bv

GNH USA supplies Ibuprofen Mae Holding Bv (Ibuprofen), a nonsteroidal anti-inflammatory drug for pain, fever and inflammation.

Ibuprofen

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What is Ibuprofen?

Ibuprofen, the active ingredient in Ibuprofen Mae Holding Bv, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It relieves mild to moderate pain, reduces fever, and diminishes inflammation associated with conditions such as arthritis in adults and children when appropriate.

GNH USA supplies Ibuprofen Mae Holding Bv as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with distribution aligned to EU regulatory standards. The company ensures product quality through rigorous testing and traceability.

What is Ibuprofen used for?

Ibuprofen is an NSAID that reduces prostaglandin‑mediated inflammation and is used for several common conditions. - Pain: provides analgesic relief for mild to moderate acute pain such as headache, dental pain, or musculoskeletal discomfort. - Fever: lowers elevated body temperature associated with infections or inflammatory states. - Inflammation: decreases swelling and redness in conditions like sprains, strains, or soft‑tissue injuries. - Arthritis: alleviates joint pain and stiffness in osteoarthritis and rheumatoid arthritis.

What are the side effects of Ibuprofen?

Ibuprofen may cause a range of adverse reactions, varying from mild to serious. Common Side Effects: - Gastrointestinal upset: nausea, dyspepsia, or heartburn may occur, especially on an empty stomach. - Headache: transient headache is reported in some users. - Dizziness: occasional light‑headedness or vertigo can be experienced. - Mild rash: skin irritation or itching may develop. Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration: severe abdominal pain or black stools require immediate medical attention. - Renal impairment: reduced kidney function may manifest as decreased urine output or swelling. - Severe hypersensitivity: anaphylaxis, angioedema, or Stevens‑Johnson syndrome demand urgent care.

What precautions apply to Ibuprofen?

When using ibuprofen, consider the following safety measures. - Assess renal function: avoid use in patients with severe kidney disease. - Monitor gastrointestinal risk: use with food or protective agents in those with ulcer history. - Avoid in known hypersensitivity: discontinue if rash or swelling occurs. - Limit use in cardiovascular disease: consider alternatives for patients with heart failure or ischemic disease. - Use caution during pregnancy: consult a healthcare provider if pregnant or planning pregnancy. - Store at ambient temperature: keep in original container, protect from moisture and heat.

What does Ibuprofen interact with?

Ibuprofen can interact with other medicines; some combinations should be avoided while others require monitoring. Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity. - Selective serotonin reuptake inhibitors (SSRIs): heightened hemorrhage risk. Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may impair renal function when combined. - Diuretics: combined use can reduce renal perfusion and increase nephrotoxicity.

Frequently asked questions

What is Ibuprofen Mae Holding Bv used for?+
Ibuprofen Mae Holding Bv contains ibuprofen, an NSAID that is used to relieve mild to moderate pain, reduce fever, and lessen inflammation associated with conditions such as arthritis, musculoskeletal injuries, and common infections.
How does ibuprofen work?+
Ibuprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the synthesis of prostaglandins. Lower prostaglandin levels decrease pain signaling, lower body temperature, and reduce swelling and redness.
What is the usual dose of Ibuprofen Mae Holding Bv?+
The appropriate dose of ibuprofen is determined by the prescribing healthcare professional based on the patient’s age, weight, condition being treated, and overall health status. Patients should follow the prescriber’s instructions and not exceed the recommended amount.
Is ibuprofen safe to use during pregnancy or breastfeeding?+
Safety of ibuprofen during pregnancy or lactation depends on the trimester and individual risk factors. It is generally avoided in the third trimester and should only be used during pregnancy or while breastfeeding if a healthcare provider determines that the benefits outweigh potential risks.
How do I order Ibuprofen Mae Holding Bv from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.
How does ibuprofen compare with other NSAIDs?+
Ibuprofen shares a similar mechanism with other non‑selective NSAIDs, providing analgesic, antipyretic and anti‑inflammatory effects. Compared with some NSAIDs, ibuprofen has a relatively short half‑life, which may allow for flexible dosing but also requires consistent administration to maintain effect.
What are the storage and handling requirements for Ibuprofen Mae Holding Bv?+
Store the product at ambient temperature, preferably below 25 °C. Keep it in the original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.
How is Ibuprofen Mae Holding Bv administered?+
The medication is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce the likelihood of gastrointestinal discomfort.
What are the most serious risks associated with ibuprofen?+
Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, and renal impairment, especially in patients with pre‑existing kidney disease or those taking other nephrotoxic agents.
Who should not use ibuprofen?+
Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, or significant renal impairment should avoid ibuprofen unless directed otherwise by a healthcare professional.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ibuprofen
Route
Oral Use
Manufacturer
Mae Holding Bv
Origin
EU

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