Europe — EMA
Ibuprofen Mae Holding Bv
GNH USA supplies Ibuprofen Mae Holding Bv (Ibuprofen), a nonsteroidal anti-inflammatory drug for pain, fever and inflammation.
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What is Ibuprofen?
Ibuprofen, the active ingredient in Ibuprofen Mae Holding Bv, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It relieves mild to moderate pain, reduces fever, and diminishes inflammation associated with conditions such as arthritis in adults and children when appropriate.
GNH USA supplies Ibuprofen Mae Holding Bv as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with distribution aligned to EU regulatory standards. The company ensures product quality through rigorous testing and traceability.
What is Ibuprofen used for?
Ibuprofen is an NSAID that reduces prostaglandin‑mediated inflammation and is used for several common conditions. - Pain: provides analgesic relief for mild to moderate acute pain such as headache, dental pain, or musculoskeletal discomfort. - Fever: lowers elevated body temperature associated with infections or inflammatory states. - Inflammation: decreases swelling and redness in conditions like sprains, strains, or soft‑tissue injuries. - Arthritis: alleviates joint pain and stiffness in osteoarthritis and rheumatoid arthritis.
What are the side effects of Ibuprofen?
Ibuprofen may cause a range of adverse reactions, varying from mild to serious. Common Side Effects: - Gastrointestinal upset: nausea, dyspepsia, or heartburn may occur, especially on an empty stomach. - Headache: transient headache is reported in some users. - Dizziness: occasional light‑headedness or vertigo can be experienced. - Mild rash: skin irritation or itching may develop. Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration: severe abdominal pain or black stools require immediate medical attention. - Renal impairment: reduced kidney function may manifest as decreased urine output or swelling. - Severe hypersensitivity: anaphylaxis, angioedema, or Stevens‑Johnson syndrome demand urgent care.
What precautions apply to Ibuprofen?
When using ibuprofen, consider the following safety measures. - Assess renal function: avoid use in patients with severe kidney disease. - Monitor gastrointestinal risk: use with food or protective agents in those with ulcer history. - Avoid in known hypersensitivity: discontinue if rash or swelling occurs. - Limit use in cardiovascular disease: consider alternatives for patients with heart failure or ischemic disease. - Use caution during pregnancy: consult a healthcare provider if pregnant or planning pregnancy. - Store at ambient temperature: keep in original container, protect from moisture and heat.
What does Ibuprofen interact with?
Ibuprofen can interact with other medicines; some combinations should be avoided while others require monitoring. Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity. - Selective serotonin reuptake inhibitors (SSRIs): heightened hemorrhage risk. Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may impair renal function when combined. - Diuretics: combined use can reduce renal perfusion and increase nephrotoxicity.
Frequently asked questions
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Product details
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