GNH USA

Europe — EMA

Ibuprofen Kabi

GNH USA supplies Ibuprofen Kabi (Ibuprofen), a nonsteroidal anti-inflammatory drug for acute and postoperative pain and fever. Request a quote for supply.

Ibuprofen

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What is Ibuprofen?

Ibuprofen, the active ingredient in Ibuprofen Kabi, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an intravenous solution for intravenous use. It is employed in hospital settings to relieve acute pain, postoperative pain, fever, and inflammatory conditions such as musculoskeletal inflammation, and related swelling among adult patients, and may be selected when oral therapy is unsuitable, providing rapid onset of analgesia.

GNH USA supplies Ibuprofen Kabi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and health‑care institutions worldwide.

What is Ibuprofen used for?

Ibuprofen Kabi is used to manage pain and inflammation through cyclo‑oxygenase inhibition.

Acute pain: provides rapid analgesia for sudden severe pain episodes. Post‑operative pain: reduces pain after surgical procedures, facilitating recovery. Fever: lowers elevated body temperature in febrile patients. Inflammatory conditions: diminishes swelling and discomfort in acute inflammatory states such as musculoskeletal injury.

What are the side effects of Ibuprofen?

Intravenous ibuprofen may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Nausea - Headache - Injection site pain

Serious or Rare Side Effects: - Severe gastrointestinal bleeding - Anaphylactic reaction - Acute renal failure

What precautions apply to Ibuprofen?

When using Ibuprofen Kabi, clinicians should observe several safety measures.

Assess renal function: evaluate baseline kidney function before use. Monitor bleeding risk: avoid in patients with active ulcer or coagulopathy. Use lowest effective dose: limit duration to reduce adverse events. Avoid in known hypersensitivity: contraindicated in patients allergic to ibuprofen or other NSAIDs. Use cautiously in cardiovascular disease: consider risk of thrombotic events. Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Ibuprofen interact with?

Ibuprofen Kabi can interact with other medicines; careful review is required.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - ACE inhibitors: reduced antihypertensive effect and potential renal impairment. - Other NSAIDs: additive gastrointestinal toxicity.

Moderate Interactions (Monitor Closely): - Diuretics: may enhance renal effects. - SSRIs: increased bleeding tendency.

Frequently asked questions

What is Ibuprofen Kabi used for?+
Ibuprofen Kabi is an intravenous formulation of ibuprofen used in hospital settings to treat acute pain, postoperative pain, fever, and short‑term inflammatory conditions. It provides rapid analgesic and antipyretic effects when oral administration is not feasible or when a fast onset of action is required.
How does ibuprofen work in Ibuprofen Kabi?+
The drug works by non‑selectively inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the synthesis of prostaglandins. Lower prostaglandin levels diminish inflammation, pain signaling, and fever generation, delivering the characteristic analgesic, antipyretic, and anti‑inflammatory actions of ibuprofen.
What is the usual dose of Ibuprofen Kabi?+
The specific dose and infusion rate are determined by the prescribing clinician based on the patient’s condition, weight, renal function, and other clinical factors. Healthcare professionals follow local guidelines and product labeling to individualise therapy for each patient.
Is Ibuprofen Kabi safe in pregnancy or breastfeeding?+
Safety data for intravenous ibuprofen during pregnancy and lactation are limited. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider after a thorough risk‑benefit assessment.
How do I order Ibuprofen Kabi from GNH USA?+
To place an order, visit the product page on gnh-usa.com, enter the required quantity, and submit the enquiry form. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.
How does Ibuprofen Kabi compare with other IV NSAIDs?+
Compared with other intravenous NSAIDs such as ketorolac, ibuprofen offers a similar analgesic profile but may have a slightly lower risk of renal toxicity at equivalent doses. Its longer half‑life can allow less frequent dosing, while ketorolac is often chosen for very short‑term, high‑intensity pain control. Choice depends on patient factors and institutional protocols.
What are the storage and handling requirements for Ibuprofen Kabi?+
Ibuprofen Kabi must be stored refrigerated at 2‑8 °C. Keep the vials in their original packaging, protect them from light, and avoid freezing or shaking the solution. If a short period at controlled room temperature is unavoidable, follow the manufacturer’s guidance on stability before use.
How is Ibuprofen Kabi administered?+
The product is supplied as a sterile intravenous solution. It is typically diluted in a compatible infusion fluid and administered over a prescribed period, often 15‑30 minutes, under aseptic conditions. Administration is performed by qualified healthcare personnel in a clinical setting.
What are the most serious risks associated with Ibuprofen Kabi?+
Serious adverse events include severe gastrointestinal bleeding, anaphylactic or severe allergic reactions, acute renal failure, and cardiovascular thrombotic events such as myocardial infarction or stroke. Patients should be monitored closely for signs of bleeding, renal dysfunction, or hypersensitivity during and after infusion.
Who should not use Ibuprofen Kabi?+
Contraindications include known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcer or bleeding, severe renal impairment, uncontrolled hypertension, and patients with a history of cardiovascular thrombotic disease where NSAID use is discouraged. Clinicians should evaluate each patient’s medical history before initiating therapy.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ibuprofen
Route
Intravenous Use
Manufacturer
Fresenius Kabi S.R.O.
Origin
EU

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