Ibuprofen

Ibuprofen, the active ingredient in Ibuprofen, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for oral use. It relieves mild to moderate pain, reduces fever, and decreases inflammation in adults and, when appropriate, in pediatric patients under medical guidance through prescribed regimens.

GNH USA supplies Ibuprofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to stringent quality standards and providing reliable global logistics. Our distribution network ensures timely delivery across Europe, Asia, Africa and the Americas.

Ibuprofen is an NSAID that reduces prostaglandin‑mediated inflammation and pain.

- Mild to moderate pain: provides analgesic relief for headaches, dental pain, musculoskeletal discomfort. - Fever: lowers elevated body temperature associated with infections or inflammatory conditions. - Osteoarthritis: alleviates joint pain and improves mobility in degenerative joint disease. - Rheumatoid arthritis: reduces joint inflammation and stiffness in autoimmune arthritis. - Dysmenorrhea: eases menstrual cramps and associated pelvic pain.

Adverse reactions may vary in frequency and severity.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia, or stomach upset. - Headache: mild to moderate intensity. - Dizziness: transient sensation of light‑headedness. - Rash: mild skin irritation or erythema.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulcer perforation. - Acute renal impairment or worsening of existing kidney disease. - Severe allergic reactions such as anaphylaxis or angioedema.

Use ibuprofen with careful consideration of individual health status. - Cardiovascular risk assessment: evaluate history of heart disease before use. - Renal function monitoring: avoid in patients with severe kidney impairment. - Dose minimisation: employ the lowest effective dose for the shortest duration. - Pregnancy caution: avoid in the third trimester and discuss use with a healthcare professional. - Gastro‑intestinal ulcer risk: consider gastro‑protective agents in high‑risk patients. - Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Ibuprofen may interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Other NSAIDs (e.g., aspirin, naproxen): additive gastrointestinal toxicity. - Corticosteroids (e.g., prednisone): heightened ulcer risk.

Moderate Interactions (Monitor Closely): - ACE inhibitors (e.g., lisinopril): possible reduction in antihypertensive effect and renal function. - Selective serotonin reuptake inhibitors (e.g., sertraline): modest increase in bleeding tendency.