Ibuprofen

Ibuprofen, the active ingredient in Ibuprofen, is a nonsteroidal anti-inflammatory drug presented as a strength/form for oral use. It treats pain, fever, inflammation and related conditions in adults and children as directed.

GNH USA supplies Ibuprofen as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen works by reducing inflammation and relieving pain across several common conditions.

Pain: Provides analgesic relief for mild to moderate pain. Fever: Lowers elevated body temperature. Inflammation: Decreases swelling in injured tissues. Headache: Alleviates tension‑type and migraine‑associated headache. Musculoskeletal pain: Reduces discomfort from strains, sprains and arthritis. Menstrual pain: Eases dysmenorrhea associated cramping.

Common Side Effects: - Gastrointestinal upset such as nausea, dyspepsia or heartburn. - Headache or dizziness. - Mild rash or itching. - Elevated blood pressure in some individuals.

Serious or Rare Side Effects: - Gastrointestinal bleeding, ulceration or perforation. - Acute kidney injury or worsening of chronic renal disease. - Severe allergic reactions including anaphylaxis or Stevens‑Johnson syndrome. - Hepatotoxicity manifested by jaundice or abnormal liver enzymes.

Before using ibuprofen, consider the following safety measures.

Assess gastrointestinal risk: evaluate history of ulcers or bleeding. Monitor renal function: avoid in patients with severe kidney impairment. Check cardiovascular status: use cautiously in those with heart disease or hypertension. Avoid use with other NSAIDs or aspirin: increases risk of adverse effects. Store at ambient temperature: keep in the original packaging, protect from moisture and heat.

Ibuprofen may interact with several medicines; awareness helps prevent complications.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened bleeding risk. - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Lithium: increased lithium serum levels. - Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: possible reduction in renal function. - Diuretics: may exacerbate fluid loss and kidney injury. - SSRIs or SNRIs: increased bleeding tendency. - Antihypertensives: potential attenuation of blood‑pressure‑lowering effect. - Oral hypoglycemics: may affect glucose control.