Ibuprofen G.L.

Ibuprofen, the active ingredient in Ibuprofen G.L., is a Non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral tablet for oral use. It relieves mild to moderate pain, reduces fever, and helps manage inflammatory conditions such as arthritis. Ibuprofen G.L. is marketed in the European Union as a generic NSAID and is supplied in compliance with international quality standards.

GNH USA supplies Ibuprofen G.L. as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen acts on inflammatory pathways and is indicated for several common conditions.

Mild to moderate pain: provides analgesic relief for headaches, dental pain, musculoskeletal aches, and postoperative discomfort. Fever: lowers elevated body temperature associated with infections or inflammatory states. Arthritis (inflammatory joint conditions): decreases joint inflammation and associated discomfort in osteoarthritis and rheumatoid arthritis.

Adverse reactions may vary in frequency and severity.

Common Side Effects: - Gastrointestinal upset (indigestion, nausea, dyspepsia) - Headache - Dizziness - Mild skin rash or itching - Elevated blood pressure in some patients - Mild renal function changes

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration - Severe allergic reactions (anaphylaxis, angioedema) - Acute renal failure or significant renal impairment - Hepatotoxicity with elevated liver enzymes - Cardiovascular events such as myocardial infarction or stroke - Severe skin reactions (Stevens‑Johnson syndrome, toxic epidermal necrolysis)

Before using ibuprofen, consider the following safety measures.

Assess gastrointestinal risk: evaluate history of ulcers, bleeding, or chronic NSAID use. Monitor renal function: especially in patients with pre‑existing kidney disease or dehydration. Avoid in third‑trimester pregnancy: risk of fetal complications and premature closure of the ductus arteriosus. Use caution with concomitant anticoagulants: increased risk of bleeding. Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Ibuprofen can interact with several medication classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened bleeding risk. - Selective serotonin reuptake inhibitors (SSRIs): increased gastrointestinal bleeding. - Lithium: potential rise in serum lithium concentrations.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce renal perfusion and function. - Diuretics: combined use can impair kidney function. - Methotrexate: reduced clearance leading to toxicity.