Ibuprofen Catalent

Ibuprofen, the active ingredient in Ibuprofen Catalent, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for systemic use. It provides analgesic, antipyretic and anti‑inflammatory effects for the relief of pain, fever and inflammation in appropriate patient populations.

GNH USA supplies Ibuprofen Catalent as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global distribution to meet the needs of healthcare providers across multiple regions.

Ibuprofen acts as an analgesic and anti‑inflammatory agent by inhibiting cyclooxygenase enzymes involved in prostaglandin synthesis.

- Pain: Reduces mild to moderate pain such as headaches, dental pain, or musculoskeletal discomfort. - Fever: Lowers elevated body temperature associated with febrile illnesses. - Inflammation: Decreases swelling and inflammation in conditions like arthritis or minor injuries.

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain. - Headache: mild to moderate intensity. - Dizziness: transient sensation of light‑headedness. - Rash: mild skin erythema or itching.

Serious or Rare Side Effects: - Gastrointestinal bleeding: ulceration or hemorrhage in the stomach or intestines. - Renal impairment: reduced kidney function or acute kidney injury. - Hepatotoxicity: elevated liver enzymes or hepatitis. - Severe hypersensitivity: anaphylaxis, angioedema or Stevens‑Johnson syndrome.

When using ibuprofen, several safety considerations should be observed to minimize risk.

- Assess renal function: avoid use in patients with severe kidney disease or dehydration. - Monitor gastrointestinal risk: use with caution in individuals with a history of ulcers or bleeding. - Evaluate cardiovascular status: limit use in patients with uncontrolled hypertension or heart failure. - Consider pregnancy and lactation: discuss risks with a healthcare professional before use. - Review concomitant medications: avoid combining with other NSAIDs or anticoagulants without guidance. - Store at ambient temperature: keep below 25 °C, protect from moisture and light in the original container.

Ibuprofen can interact with other medicines, altering their effectiveness or safety profile.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - High‑dose aspirin: heightened gastrointestinal toxicity. - Selective serotonin reuptake inhibitors (SSRIs): elevated bleeding risk.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce renal protective effects. - Diuretics: potential for reduced diuretic efficacy and kidney function. - Lithium: ibuprofen may increase lithium serum levels. - Methotrexate: possible increase in methotrexate toxicity.