Ibuprofen Catalent

Ibuprofen, the active ingredient in Ibuprofen Catalent, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is used to relieve pain, reduce fever, and diminish inflammation in adults and children when appropriate.

GNH USA supplies Ibuprofen Catalent as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen acts on the cyclooxygenase pathway to provide analgesic, antipyretic, and anti‑inflammatory effects.

- Pain: Reduces mild to moderate pain such as headache, dental pain, or musculoskeletal discomfort. - Fever: Lowers elevated body temperature associated with infections or inflammatory conditions. - Inflammation: Decreases swelling and stiffness in conditions like arthritis or soft‑tissue injuries.

Ibuprofen may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain. - Headache: mild to moderate tension‑type headache. - Dizziness: transient light‑headedness or vertigo. - Rash: mild skin erythema or itching.

Serious or Rare Side Effects: - Gastrointestinal bleeding: ulceration or hemorrhage in the stomach or intestines. - Renal impairment: sudden decrease in kidney function or fluid retention. - Severe hypersensitivity: anaphylaxis, angioedema, or Stevens‑Johnson syndrome.

When considering ibuprofen therapy, several safety measures should be observed.

- Assess renal function: avoid use in patients with severe kidney disease or dehydration. - Monitor gastrointestinal risk: use caution in individuals with a history of ulcers or bleeding. - Evaluate cardiovascular status: limit use in patients with uncontrolled hypertension or heart failure. - Review concomitant medications: avoid concurrent use with other NSAIDs, anticoagulants, or corticosteroids without supervision. - Pregnancy and lactation: consult a healthcare professional before use during pregnancy or breastfeeding. - Store at ambient temperature: keep below 25°C in the original container, protect from moisture and direct sunlight.

Ibuprofen can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - High‑dose aspirin: heightened gastrointestinal toxicity. - Selective COX‑2 inhibitors: additive renal and cardiovascular adverse effects.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce antihypertensive effect and impair renal function. - Diuretics: potential for reduced diuretic efficacy and electrolyte imbalance. - Lithium: ibuprofen can raise lithium serum concentrations, risking toxicity.