Ibuprofen Bristol Laboratories

Ibuprofen, the active ingredient in Ibuprofen Bristol Laboratories, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It treats pain, fever, inflammation and arthritis in adults and children as directed by a healthcare professional.

GNH USA supplies Ibuprofen Bristol Laboratories as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen acts as an analgesic and antipyretic within the NSAID drug class, reducing inflammation and pain.

- Pain: Provides relief for mild to moderate acute pain such as headache, dental or musculoskeletal discomfort. - Fever: Lowers elevated body temperature associated with infections or inflammatory conditions. - Inflammation: Decreases swelling and redness in conditions like sprains or minor injuries. - Arthritis: Alleviates joint pain and stiffness in osteoarthritis and rheumatoid arthritis.

Adverse reactions may vary in frequency and severity.

Common Side Effects: - Nausea: mild stomach upset or queasiness. - Dyspepsia: indigestion or heartburn. - Headache: transient mild headache. - Dizziness: occasional light‑headed feeling. - Rash: mild skin irritation or itching. - Diarrhoea: loose stools.

Serious or Rare Side Effects: - Gastrointestinal bleeding: black stools or vomiting blood. - Peptic ulcer: persistent abdominal pain. - Renal impairment: reduced urine output or swelling. - Severe allergic reaction: swelling of face, lips, or throat, difficulty breathing. - Hepatic injury: jaundice or abnormal liver tests.

Before using ibuprofen, consider the following safety measures.

- Assess renal function: evaluate kidney health, especially in the elderly or dehydrated patients. - Evaluate gastrointestinal risk: avoid in individuals with active ulcers or history of GI bleeding. - Review cardiovascular status: use cautiously in patients with hypertension or heart disease. - Monitor concomitant medications: check for drugs that increase bleeding risk. - Avoid use in late pregnancy: discuss alternatives with a healthcare provider. - Store at below 25°C: keep in the original pack, protect from moisture and direct sunlight.

Ibuprofen can affect the activity of several other medicines.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Other NSAIDs: additive gastrointestinal toxicity. - Lithium: higher lithium serum concentrations.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: possible reduction in antihypertensive effect. - Diuretics: may diminish diuretic efficacy and affect kidney function. - SSRIs: heightened risk of gastrointestinal bleeding.