Ibuprofen Brillpharma (Ireland)

Ibuprofen, the active ingredient in Ibuprofen Brillpharma, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is used to relieve pain, reduce fever, and control inflammation in adults and children when appropriate.

GNH USA supplies Ibuprofen Brillpharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen acts as an NSAID to manage symptoms associated with inflammatory and febrile conditions. - Pain relief: reduces mild to moderate pain such as headache, dental or musculoskeletal discomfort. - Fever reduction: lowers elevated body temperature caused by infection or inflammation. - Inflammation control: diminishes swelling and stiffness in conditions like arthritis or soft‑tissue injury.

Adverse reactions may vary in frequency and severity.

Common Side Effects: - Gastrointestinal upset: nausea, dyspepsia, or heartburn. - Headache or dizziness. - Mild skin rash. - Elevated blood pressure.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration. - Severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome. - Acute kidney injury or worsening of chronic renal disease. - Hepatotoxicity with marked liver enzyme elevation. - Cardiovascular events including myocardial infarction or stroke. - Hematologic abnormalities like thrombocytopenia.

Before using Ibuprofen, consider the following safety measures. - Renal function assessment: evaluate kidney health, especially in the elderly or those with chronic disease. - Lowest effective dose: use the smallest dose needed for symptom control to limit adverse effects. - Hypersensitivity caution: avoid if a known allergy to ibuprofen or other NSAIDs exists. - Anticoagulant interaction: monitor bleeding risk when combined with warfarin, aspirin, or similar agents. - Gastrointestinal monitoring: watch for signs of ulceration or bleeding, particularly with prolonged use. - Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Ibuprofen can affect the activity of several other medicines.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - High‑dose aspirin: heightened gastrointestinal toxicity. - Selective serotonin reuptake inhibitors (SSRIs): elevated bleeding potential.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce renal perfusion, especially in volume‑depleted patients. - Diuretics: possible decrease in antihypertensive effect and renal function. - Lithium: ibuprofen can raise lithium levels, requiring serum monitoring.