Ibuprofen B. Braun

Ibuprofen, the active ingredient in Ibuprofen B. Braun, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an intravenous formulation for parenteral use. It treats pain, fever and inflammation in adult patients, including postoperative settings.

GNH USA supplies Ibuprofen B. Braun as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen, an NSAID that reduces prostaglandin‑mediated inflammation, is indicated for the following conditions:

- Pain: provides analgesia for mild to moderate acute pain. - Fever: lowers elevated body temperature. - Inflammation: reduces swelling and inflammatory response. - Postoperative pain: manages pain following surgical procedures.

Adverse reactions may occur with intravenous ibuprofen use.

Common Side Effects: - Nausea - Dyspepsia - Headache - Dizziness - Injection‑site pain or erythema - Transient increase in serum creatinine

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration - Severe renal impairment - Anaphylactic or severe hypersensitivity reactions - Stevens‑Johnson syndrome or toxic epidermal necrolysis - Cardiovascular thrombotic events such as myocardial infarction - Hepatotoxicity

When using intravenous ibuprofen, consider the following precautions:

- Renal function: monitor in patients with existing renal impairment. - Hepatic function: use cautiously in liver disease. - Cardiovascular risk: avoid in patients with active coronary artery disease. - Bleeding risk: assess before surgical or invasive procedures. - Pregnancy: avoid unless benefits outweigh potential risks. - Store at ambient temperature: keep in original packaging, protect from moisture and light.

Ibuprofen may interact with several medicines; awareness of these interactions helps ensure safe use.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened risk of bleeding. - ACE inhibitors (e.g., lisinopril): possible decline in renal function. - Lithium: increased serum lithium concentrations.

Moderate Interactions (Monitor Closely): - SSRIs (e.g., sertraline): additive bleeding tendency. - Diuretics (e.g., furosemide): may affect renal clearance.