Ibuprofen B. Braun

Ibuprofen, the active ingredient in Ibuprofen B. Braun, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an intravenous solution for intravenous use. It treats mild to moderate pain, fever, inflammation, and post‑operative pain in hospital patients.

GNH USA supplies Ibuprofen B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, clinics and healthcare institutions worldwide.

Ibuprofen is an NSAID that reduces pain, fever, and inflammation by inhibiting prostaglandin synthesis.

- Mild to moderate pain: provides analgesia for surgical or injury‑related discomfort. - Fever: lowers elevated body temperature. - Inflammation: decreases swelling associated with postoperative or musculoskeletal conditions.

Adverse reactions may occur with intravenous ibuprofen administration.

Common Side Effects: - Nausea or vomiting. - Headache. - Transient rise in blood pressure. - Injection site discomfort or phlebitis.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration. - Acute kidney injury, especially in volume‑depleted patients. - Severe hypersensitivity reactions such as anaphylaxis or Stevens‑Johnson syndrome.

Use ibuprofen intravenously only under professional supervision and consider patient‑specific risk factors.

- Renal function: assess baseline creatinine and avoid in severe renal impairment. - Cardiovascular risk: monitor blood pressure and avoid in uncontrolled hypertension. - Gastrointestinal history: use cautiously in patients with ulcer disease or bleeding disorders. - Coagulation status: be aware of increased bleeding risk, especially with anticoagulants. - Pregnancy and lactation: evaluate risk‑benefit ratio; data are limited for IV use. - Store at ambient temperature: keep in original container, protect from light and moisture.

Ibuprofen may interact with several drug classes, requiring clinical awareness.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): may amplify bleeding risk. - High‑dose aspirin or other NSAIDs: can increase nephrotoxicity and gastrointestinal injury.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce renal perfusion, especially in dehydrated patients. - Diuretics: combined use can impair renal function. - Lithium: ibuprofen can raise serum lithium levels. - Methotrexate: may decrease renal clearance, raising toxicity risk.