Ibuprofen Al

Ibuprofen, the active ingredient in Ibuprofen Al, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as a tablet for oral use. It treats pain, fever and inflammation in adults and children as appropriate.

GNH USA supplies Ibuprofen Al as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen is an NSAID that reduces pain, fever and inflammatory processes. - Pain: provides relief of mild to moderate acute pain such as headache, dental or musculoskeletal discomfort. - Fever: lowers elevated body temperature associated with infections or inflammatory conditions. - Inflammation: diminishes swelling and stiffness in conditions like arthritis or soft‑tissue injury.

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects: - Gastrointestinal upset: nausea, dyspepsia or abdominal discomfort. - Headache: mild to moderate intensity. - Dizziness or vertigo. - Skin rash or mild itching. - Elevated blood pressure in susceptible individuals.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulcer perforation. - Acute renal failure or worsening of chronic kidney disease. - Severe hypersensitivity reactions including anaphylaxis. - Hepatotoxicity with elevated liver enzymes. - Cardiovascular events such as myocardial infarction or stroke, particularly with high‑dose or prolonged use.

Before initiating ibuprofen therapy, consider patient‑specific risk factors and monitor appropriately. - Assess gastrointestinal risk: avoid in patients with active ulcer disease or a history of GI bleeding. - Monitor renal function: use caution in those with impaired kidney function or dehydration. - Use the lowest effective dose for the shortest duration needed. - Avoid in individuals with known hypersensitivity to ibuprofen or other NSAIDs. - Caution when combined with anticoagulants or antiplatelet agents. - Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Ibuprofen can interact with several drug classes, influencing safety and efficacy.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Corticosteroids: heightened risk of ulceration. - Lithium: possible increase in lithium serum levels. - Methotrexate: reduced renal clearance leading to toxicity.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: potential reduction in renal function. - Diuretics: may exacerbate renal impairment. - Selective serotonin reuptake inhibitors (SSRIs): increased bleeding tendency. - Antihypertensive agents: possible attenuation of blood‑pressure‑lowering effect. - Antidiabetic drugs: may affect glycaemic control.