Ibuprofen Actavis

Ibuprofen, the active ingredient in Ibuprofen Actavis, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a tablet for oral use. It relieves mild to moderate pain, reduces fever, and decreases inflammation in adults and children as appropriate.

GNH USA supplies Ibuprofen Actavis as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen is an NSAID that reduces inflammation and pain by inhibiting cyclooxygenase enzymes.

- Mild to moderate pain: provides analgesic relief for headaches, dental pain, musculoskeletal discomfort. - Fever: lowers elevated body temperature. - Osteoarthritis: helps manage chronic joint pain and stiffness. - Rheumatoid arthritis: reduces inflammation and pain associated with the disease.

Ibuprofen may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain. - Headache: mild to moderate intensity. - Dizziness: transient sensation of light‑headedness. - Rash: mild skin irritation or itching.

Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding: potentially life‑threatening. - Severe hypersensitivity: anaphylaxis or angioedema. - Renal impairment: acute kidney injury, especially with dehydration. - Hepatotoxicity: elevated liver enzymes or jaundice.

Before using Ibuprofen Actavis, consider the following safety measures.

- Assess renal function: avoid use in severe kidney disease without medical supervision. - Monitor cardiovascular risk: use cautiously in patients with hypertension or heart disease. - Avoid in active peptic ulcer: risk of bleeding may increase. - Limit alcohol consumption: may enhance gastrointestinal irritation. - Check for drug allergies: discontinue if signs of hypersensitivity appear. - Store at ambient temperature: keep below 25°C in original packaging, protect from moisture.

Ibuprofen can interact with other medicines, affecting efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - High‑dose aspirin: additive gastrointestinal toxicity. - Selective COX‑2 inhibitors: heightened cardiovascular risk. - ACE inhibitors or ARBs: may reduce renal protective effects. - Lithium: NSAIDs can raise lithium levels.

Moderate Interactions (Monitor Closely): - Diuretics: may diminish diuretic response. - Methotrexate: possible increased toxicity. - Corticosteroids: higher ulcer risk. - SSRIs or SNRIs: elevated bleeding potential. - Antihypertensives: may blunt blood pressure control.