Nurofen Για Παιδιά (Πορτοκάλι) (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Για Παιδιά (Πορτοκάλι), is a nonsteroidal anti‑inflammatory drug (NSAID) presented as an oral suspension for oral use. It provides pain relief, reduces fever, and alleviates inflammation in children, and is commonly used for mild to moderate discomfort.

GNH USA supplies Nurofen Για Παιδιά (Πορτοκάλι) as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product complies with EU regulatory standards and is manufactured under Good Manufacturing Practices.

Ibuprofen is an NSAID that reduces prostaglandin‑mediated pain, fever, and inflammation in children.

- Fever: lowers elevated body temperature in pediatric patients. - Pain: relieves mild to moderate pain such as headache, toothache, sore throat, or post‑vaccination discomfort. - Inflammation: diminishes swelling associated with minor injuries, sprains, or musculoskeletal strain.

Common Side Effects: - Stomach upset or dyspepsia - Nausea or vomiting - Diarrhoea - Mild skin rash or itching - Headache - Dizziness

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration - Severe allergic reactions including anaphylaxis - Kidney function impairment - Liver enzyme elevation or hepatitis - Stevens‑Johnson syndrome or toxic epidermal necrolysis - Blood disorders such as thrombocytopenia

Before using ibuprofen in children, consider the following precautions: - Age restriction: use only in children as directed by a healthcare professional. - Allergy warning: avoid if the child has known hypersensitivity to ibuprofen or other NSAIDs. - Medical conditions: exercise caution in children with asthma, renal, hepatic or cardiovascular disease. - Concomitant medications: do not combine with other NSAIDs, anticoagulants, or corticosteroids without medical advice. - Pregnancy and lactation: not recommended during the third trimester of pregnancy; consult a physician if breastfeeding. - Store below 25°C: keep in the original pack, protect from moisture and direct sunlight.

Ibuprofen can interact with several medicines; monitoring is essential.

Major Interactions (Avoid): - Anticoagulants such as warfarin: increased risk of bleeding. - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Corticosteroids: heightened risk of ulceration. - ACE inhibitors or ARBs in children with renal impairment: possible reduction in renal function. - Lithium: ibuprofen may raise lithium serum levels.

Moderate Interactions (Monitor Closely): - Diuretics: may reduce renal clearance of ibuprofen. - Methotrexate: potential for increased toxicity. - Antihypertensives: ibuprofen can attenuate their effect. - SSRIs: modest increase in bleeding risk. - Oral hypoglycemics: possible alteration of blood glucose control.