GNH USA

Europe — EMA

Nurofen Pro Děti Active (Ibuprofen)

GNH USA supplies Nurofen Pro Děti Active (Ibuprofen), a non‑steroidal anti‑inflammatory drug for fever and pain relief in children.

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What is Ibuprofen?

Ibuprofen, the active ingredient in Nurofen Pro Děti Active, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as a pediatric oral formulation for use in children. It provides analgesic and antipyretic effects, helping to relieve pain and reduce fever in the pediatric population, and is commonly used for mild to moderate discomfort such as toothache, sore throat, or musculoskeletal pain.

GNH USA supplies Nurofen Pro Děti Active as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, including pediatric care centers.

What is Ibuprofen used for?

Ibuprofen, an NSAID, is used to manage inflammation‑related symptoms and fever in pediatric patients.

- Fever: reduces elevated body temperature in children. - Headache: alleviates mild to moderate headache pain. - Toothache: provides relief from dental pain. - Musculoskeletal pain: eases discomfort from sprains, strains or minor injuries. - Post‑vaccination discomfort: reduces pain and fever following immunizations.

What are the side effects of Ibuprofen?

Common Side Effects: - Nausea: mild stomach upset after oral intake. - Vomiting: occasional expulsion of stomach contents. - Abdominal pain: discomfort or cramps in the stomach area. - Diarrhea: loose stools occurring after dosing. - Headache: mild to moderate head pain. - Dizziness: transient feeling of light‑headedness.

Serious or Rare Side Effects: - Gastrointestinal bleeding: blood in stool or vomit. - Peptic ulceration: painful sores in the stomach or intestines. - Severe allergic reactions: rash, angioedema, or anaphylaxis. - Liver enzyme elevation: signs of hepatic stress. - Renal impairment: reduced urine output or swelling. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

What precautions apply to Ibuprofen?

Before using Nurofen Pro Děti Active, consider the following precautions: - Assess for allergy: avoid if the child has known hypersensitivity to ibuprofen or other NSAIDs. - Monitor gastrointestinal risk: use with caution in children with a history of ulcers or bleeding disorders. - Evaluate renal function: do not use in dehydrated children or those with existing kidney disease. - Avoid concomitant aspirin: combined use may increase the risk of Reye's syndrome. - Limit duration: employ the shortest effective treatment period. - Store at ambient temperature: keep below 25°C, protect from moisture and light, and retain in the original packaging.

What does Ibuprofen interact with?

Ibuprofen can interact with several medicines; awareness of these interactions helps ensure safe use.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Other NSAIDs: additive gastrointestinal toxicity. - Corticosteroids: heightened chance of ulcer formation.

Moderate Interactions (Monitor Closely): - ACE inhibitors or diuretics: may affect renal function. - Lithium: ibuprofen can raise lithium serum levels. - Methotrexate: reduced clearance leading to toxicity.

Frequently asked questions

What is Nurofen Pro Děti Active used for?+
Nurofen Pro Děti Active is an ibuprofen‑based medication indicated for the temporary relief of mild to moderate pain and reduction of fever in children. It is commonly employed for conditions such as headache, toothache, sore throat, musculoskeletal discomfort, and post‑vaccination fever.
How does ibuprofen work?+
Ibuprofen inhibits the cyclooxygenase enzymes COX‑1 and COX‑2, which are responsible for converting arachidonic acid into prostaglandins. By reducing prostaglandin synthesis, it decreases inflammation, pain signaling, and the hypothalamic set‑point for temperature, thereby providing analgesic and antipyretic effects.
What is the usual dose?+
The exact dose of Nurofen Pro Děti Active is determined by the prescribing healthcare professional based on the child’s age, weight, and clinical condition. The prescriber will calculate the appropriate milligram amount per kilogram and provide dosing instructions on the product label.
Is it safe during pregnancy or breastfeeding?+
Ibuprofen is generally not recommended during the third trimester of pregnancy because it may affect fetal cardiovascular function. For breastfeeding mothers, short‑term use is considered compatible, but the prescriber should evaluate the risk‑benefit ratio and advise accordingly.
How do I order Nurofen Pro Děti Active from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does it compare with the main alternative drug?+
The primary alternative to ibuprofen in children is paracetamol (acetaminophen). While both provide antipyretic and analgesic effects, ibuprofen additionally possesses anti‑inflammatory activity and may be more effective for musculoskeletal pain. However, ibuprofen carries a higher risk of gastrointestinal irritation, whereas paracetamol has a lower GI profile but can affect liver function at high doses.
What are the storage and handling requirements?+
Nurofen Pro Děti Active should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and do not use it after the expiration date indicated on the label.
How is the medication administered?+
The product is intended for oral administration. The prescribed dose is usually measured using a calibrated dosing device such as a syringe or measuring cup provided with the medication. It should be given directly into the mouth and can be taken with or without food, as advised by the prescriber.
What are the most serious risks to watch for?+
Serious adverse reactions to ibuprofen in children include gastrointestinal bleeding or ulceration, severe allergic responses such as anaphylaxis or angioedema, and renal impairment, especially in dehydrated or ill patients. Any signs of rash, swelling, blood in stool, or reduced urine output require immediate medical attention.
Who should not use Nurofen Pro Děti Active?+
Children with a known hypersensitivity to ibuprofen, other NSAIDs, or aspirin should avoid this medication. It is also contraindicated in children with active gastrointestinal ulcer disease, severe renal or hepatic impairment, and in those who have experienced Reye’s syndrome after viral infection.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ibuprofen
Route
Oral Use
Manufacturer
Reckitt Benckiser (Czech Republic) Spol. S.R.O
Origin
EU

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