GNH USA

Europe — EMA

Ibuprofeno Stada 400 Mg Comprimidos Revestidos Por Película

GNH USA supplies Ibuprofeno Stada 400 Mg Comprimidos Revestidos Por Película (Ibuprofen), a nonsteroidal anti‑inflammatory drug for pain, fever

Ibuprofen

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What is Ibuprofen?

Ibuprofen, the active ingredient in Ibuprofeno Stada 400 Mg Comprimidos Revestidos Por Película, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a 400 mg film‑coated tablet for oral use. It provides analgesic, antipyretic and anti‑inflammatory effects for the relief of mild to moderate pain, fever and inflammation in adults.

GNH USA supplies Ibuprofeno Stada 400 Mg Comprimidos Revestidos Por Película as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ibuprofen used for?

Ibuprofen is an NSAID that reduces pain, fever and inflammation by inhibiting prostaglandin synthesis.

- Headache: alleviates pain associated with tension or migraine. - Dental pain: reduces postoperative discomfort. - Musculoskeletal pain: eases aches from sprains, strains or arthritis. - Fever: lowers elevated body temperature. - Menstrual cramps: diminishes dysmenorrhea pain.

What are the side effects of Ibuprofen?

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Nausea: mild stomach upset. - Dyspepsia: indigestion or discomfort. - Headache: transient cranial pain. - Diarrhea: loose stools.

Serious or Rare Side Effects: - Gastrointestinal ulcer or bleeding: severe stomach or intestinal lesions. - Renal impairment: reduced kidney function. - Anaphylaxis: severe allergic reaction.

What precautions apply to Ibuprofen?

When using ibuprofen, several precautions should be observed to minimize risk. - Assess renal function: avoid use in patients with severe kidney disease. - Evaluate cardiovascular risk: use cautiously in individuals with heart disease or hypertension. - Review gastrointestinal history: avoid in those with active ulcers or bleeding disorders. - Monitor pregnancy: avoid unless clearly needed, as safety data are limited. - Store at ambient temperature: keep below 25 °C, retain in original packaging and protect from moisture.

What does Ibuprofen interact with?

Ibuprofen can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - High‑dose aspirin: heightened gastrointestinal toxicity. - ACE inhibitors or ARBs: may reduce renal protective effects.

Moderate Interactions (Monitor Closely): - Diuretics: possible reduction in diuretic effectiveness. - Lithium: increased lithium levels. - Methotrexate: reduced clearance leading to toxicity.

Frequently asked questions

What is Ibuprofeno Stada 400 Mg used for?+
It is an oral NSAID indicated for relief of mild to moderate pain, reduction of fever, and alleviation of inflammation associated with conditions such as headache, dental pain, musculoskeletal discomfort, and menstrual cramps. It is available over‑the‑counter and intended for adult use unless otherwise directed by a healthcare professional.
How does ibuprofen work?+
Ibuprofen works by non‑selectively inhibiting the cyclooxygenase‑1 and cyclo‑oxygenase‑2 enzymes, which blocks the conversion of arachidonic acid into prostaglandins and thromboxanes. The reduction in prostaglandin synthesis diminishes inflammation, pain signaling, and the hypothalamic response that raises body temperature, providing analgesic, antipyretic, and anti‑inflammatory effects.
What determines the dose of Ibuprofeno Stada 400 Mg?+
The appropriate dose of ibuprofen is determined by the prescribing clinician based on the severity of symptoms, patient age, weight, renal and hepatic function, and any concomitant medications. The product is supplied as 400 mg tablets, and the prescriber will specify the number of tablets and dosing interval appropriate for each individual case.
Is ibuprofen safe during pregnancy or breastfeeding?+
Safety of ibuprofen in pregnancy is not fully established; it is generally avoided during the third trimester because of potential fetal cardiovascular effects. During lactation, small amounts may pass into breast milk, and caution is advised. Women who are pregnant, planning pregnancy, or breastfeeding should consult their healthcare provider before using ibuprofen.
How do I order Ibuprofeno Stada 400 Mg from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, indicating the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide and will request verification of trade or institutional credentials. After confirmation, the sales team provides pricing, availability, shipping details (including any required import documentation) and finalizes the transaction.
How does ibuprofen compare with acetaminophen?+
Ibuprofen and acetaminophen are both OTC analgesics, but they differ in mechanism and therapeutic profile. Ibuprofen is an NSAID that reduces inflammation in addition to pain and fever, whereas acetaminophen primarily provides analgesic and antipyretic effects without significant anti‑inflammatory activity. Ibuprofen may cause gastrointestinal or renal side effects, while acetaminophen carries a risk of liver toxicity at high doses. Choice depends on the clinical situation and patient tolerance.
What are the recommended storage conditions for Ibuprofeno Stada 400 Mg?+
Ibuprofeno Stada 400 mg film‑coated tablets should be stored at ambient temperature, preferably below 25 °C (77 °F). Keep the tablets in the original blister pack or container, protect them from moisture, excessive heat and direct sunlight. Do not store in the bathroom or near a kitchen sink, and keep out of reach of children.
How is Ibuprofeno Stada 400 Mg administered?+
The medication is taken orally with a full glass of water. Tablets may be swallowed with or without food; taking them with food can lessen mild gastrointestinal discomfort. The tablet should not be chewed, crushed, or dissolved unless specifically instructed by a healthcare professional. Follow the prescriber’s directions regarding the number of tablets per dose and the interval between doses.
What are the most serious risks associated with ibuprofen use?+
The most serious risks include gastrointestinal bleeding or ulceration, which can be life‑threatening, especially in patients with a history of ulcers or concurrent anticoagulant therapy. Renal impairment or failure may occur, particularly in individuals with pre‑existing kidney disease or dehydration. Severe allergic reactions such as anaphylaxis and cardiovascular events like heart attack or stroke are also rare but critical concerns that require immediate medical attention.
Who should avoid using ibuprofen?+
Ibuprofen should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcer or bleeding, severe renal or hepatic impairment, uncontrolled hypertension, and in the third trimester of pregnancy. Patients on anticoagulants, certain antihypertensive agents, or those with a history of cardiovascular disease should consult a healthcare professional before using ibuprofen. Children under the recommended age for the specific formulation should not use adult 400 mg tablets.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Ibuprofen
Route
Oral Use
Manufacturer
Stada Lda.
Origin
EU

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