Ibumal

Ibuprofen, the active ingredient in Ibumal, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral dosage form for oral use. It provides analgesic, antipyretic and anti‑inflammatory effects for adults and children when appropriate.

GNH USA supplies Ibumal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen acts systemically to reduce inflammation and pain across several common conditions.

Mild to moderate pain: provides analgesic relief for headaches, dental pain, musculoskeletal aches, and menstrual cramps. Fever: lowers elevated body temperature associated with infections or inflammatory states. Arthritis and other inflammatory conditions: diminishes joint swelling and improves mobility in osteoarthritis and rheumatoid arthritis.

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain. - Headache: mild to moderate intensity. - Dizziness or vertigo. - Skin rash or mild itching.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration. - Acute renal impairment or worsening of chronic kidney disease. - Severe hypersensitivity reactions, including anaphylaxis. - Hepatotoxicity with elevated liver enzymes. - Thrombocytopenia or other hematologic abnormalities. - Cardiovascular events such as myocardial infarction in high‑risk patients.

Before initiating ibuprofen therapy, consider patient‑specific risk factors and appropriate monitoring.

Assess renal function: avoid or adjust dose in patients with severe kidney impairment. Evaluate gastrointestinal risk: use caution in individuals with a history of ulcers or bleeding. Monitor cardiovascular status: limit use in patients with established heart disease or uncontrolled hypertension. Check for asthma sensitivity: ibuprofen can exacerbate bronchospasm in aspirin‑sensitive asthmatics. Avoid use during the third trimester of pregnancy: potential fetal complications. Store at ambient temperature: keep below 25 °C in the original container, protected from moisture and direct sunlight.

Ibuprofen can alter the effectiveness or safety profile of several co‑administered medicines.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Other NSAIDs or aspirin: heightened gastrointestinal toxicity.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce antihypertensive effect and impair kidney function. - Lithium: ibuprofen can raise lithium serum concentrations. - Methotrexate: reduced clearance may lead to toxicity. - Selective serotonin reuptake inhibitors (SSRIs): modestly increased bleeding risk.