GNH USA

Europe — EMA

Ibugard

GNH USA supplies Ibugard (Ibuprofen), a non-steroidal anti-inflammatory drug for pain, fever and inflammation. Request a quote for global worldwide supply.

Ibuprofen

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What is Ibuprofen?

Ibuprofen, the active ingredient in Ibugard, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as a suppository for rectal use. It provides analgesic, antipyretic and anti‑inflammatory effects for the relief of mild to moderate pain, fever and inflammatory conditions, especially when oral administration is not feasible.\n\nGNH India supplies Ibugard as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and procurement teams worldwide, ensuring consistent quality and regulatory compliance across markets.

What is Ibuprofen used for?

Ibuprofen acts systemically to reduce prostaglandin‑mediated inflammation, providing relief in several common conditions.\n\n- Pain: alleviates mild to moderate acute pain such as headache, dental pain, musculoskeletal discomfort.\n- Fever: reduces elevated body temperature associated with infections or inflammatory states.\n- Inflammation: diminishes swelling and tenderness in minor sprains, strains and soft‑tissue injuries.

What are the side effects of Ibuprofen?

Rectal ibuprofen may cause a range of adverse reactions, varying from mild to serious.\n\nCommon Side Effects:\n- Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.\n- Local irritation: burning or itching at the insertion site.\n- Headache: mild tension‑type headache.\n- Dizziness: transient light‑headedness.\n\nSerious or Rare Side Effects:\n- Gastrointestinal bleeding: ulceration or hemorrhage.\n- Renal impairment: reduced kidney function or acute renal failure.\n- Allergic reactions: rash, angio‑edema or anaphylaxis.\n- Cardiovascular events: increased risk of heart attack or stroke.

What precautions apply to Ibuprofen?

Before using Ibugard, consider the following precautions to ensure safe use.\n\n- Assess renal function: avoid use in patients with severe kidney disease.\n- Monitor gastrointestinal risk: use with caution in individuals with ulcer history.\n- Evaluate cardiovascular status: consider risk in patients with heart disease.\n- Use in pregnancy only if clearly needed: limited data for rectal ibuprofen.\n- Avoid in children under 6 months unless directed: dosing not established.\n- Store at room temperature: keep in original packaging, protect from moisture and heat.

What does Ibuprofen interact with?

Ibuprofen can interact with several medicines; awareness helps prevent adverse outcomes.\n\nMajor Interactions (Avoid):\n- Anticoagulants (e.g., warfarin): increased bleeding risk.\n- Other NSAIDs or aspirin: heightened gastrointestinal toxicity.\n- SSRIs: potential for bleeding.\n\nModerate Interactions (Monitor Closely):\n- ACE inhibitors or ARBs: may affect renal function.\n- Lithium: ibuprofen can raise lithium concentrations.\n- Methotrexate: risk of increased toxicity.

Frequently asked questions

What is Ibugard used for?+
Ibugard is a rectal suppository containing ibuprofen, an NSAID. It is used to relieve mild to moderate pain, reduce fever, and decrease inflammation, especially when oral administration is not possible or not preferred, such as in patients who are vomiting or have difficulty swallowing.
How does ibuprofen work?+
Ibuprofen works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are required for the conversion of arachidonic acid into prostaglandins. By lowering prostaglandin levels, it reduces inflammation, pain signalling, and the hypothalamic set‑point for body temperature, providing analgesic, antipyretic and anti‑inflammatory effects.
What is the usual dose of Ibugard?+
The appropriate dose of Ibugard is determined by a qualified prescriber based on the patient’s age, weight, clinical condition and the severity of symptoms. The prescriber will select the correct strength and frequency of administration in accordance with local guidelines and product labeling.
Is Ibugard safe during pregnancy or breastfeeding?+
Safety data for rectal ibuprofen in pregnancy are limited, and it should only be used if the potential benefit justifies any potential risk to the fetus. Ibuprofen can be excreted in breast milk; therefore, nursing mothers should consult a healthcare professional before using Ibugard.
How do I order Ibugard from GNH USA?+
To place an order, submit an enquiry on the Ibugard product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Ibugard compare with other NSAIDs?+
Ibugard delivers ibuprofen via the rectal route, which can provide faster systemic absorption and avoid gastrointestinal irritation associated with oral NSAIDs. Compared with other NSAIDs such as naproxen or diclofenac, ibuprofen has a well‑established safety profile, but the choice of agent depends on individual patient factors, dosing convenience and specific clinical indications.
How should I store Ibugard?+
Store Ibugard at room temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Do not freeze the suppositories, and keep them out of reach of children. Proper storage helps maintain product stability and efficacy.
How is Ibugard administered?+
Ibugard is inserted rectally, typically using a gloved finger or an applicator if provided. The suppository should be placed gently into the rectum, preferably after a bowel movement, and the patient should remain lying down for a few minutes to ensure proper absorption. Follow the prescriber’s instructions for frequency.
What are the most serious risks associated with Ibugard?+
The most serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment leading to acute kidney injury, and increased cardiovascular events like heart attack or stroke. Patients should be monitored for signs of these reactions and seek immediate medical attention if they occur.
Who should not use Ibugard?+
Ibugard should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, patients with severe renal or hepatic impairment, and anyone who has experienced a serious cardiovascular event while using NSAIDs. It is also contraindicated in children for whom the appropriate rectal dose has not been established.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ibuprofen
Route
Rectal Use
Manufacturer
Zaklady Farmaceutyczne Polpharma S.A.
Origin
EU

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