GNH USA

Europe — EMA

Ibudex

GNH USA supplies Ibudex (Ibuprofen), a nonsteroidal anti-inflammatory drug for pain, fever and inflammation.

Ibuprofen

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What is Ibuprofen?

Ibuprofen, the active ingredient in Ibudex, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for systemic use. It relieves mild to moderate pain, reduces fever, and eases inflammation in conditions such as headache, arthritis, and dysmenorrhea.

GNH USA supplies Ibudex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality manufacturing, regulatory compliance, and reliable distribution across multiple markets, and providing comprehensive documentation for importers. Our global network facilitates timely delivery and post‑sale support to meet customer needs.

What is Ibuprofen used for?

Ibuprofen, an NSAID, reduces pain and inflammation by inhibiting prostaglandin synthesis. - Headache: provides relief from mild to moderate tension‑type or migraine‑associated pain. - Dental pain: alleviates discomfort following dental procedures or toothaches. - Musculoskeletal pain: eases aches from strains, sprains, or osteoarthritis. - Fever: lowers elevated body temperature in acute febrile states. - Dysmenorrhea: reduces menstrual cramps and associated pelvic pain.

What are the side effects of Ibuprofen?

Common and serious adverse reactions have been reported with ibuprofen use.

Common Side Effects: - Stomach upset or dyspepsia. - Heartburn or acid reflux. - Nausea. - Dizziness. - Headache. - Mild skin rash.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulcer formation. - Acute kidney injury. - Severe allergic reaction (anaphylaxis). - Elevated liver enzymes. - Increased risk of cardiovascular events such as heart attack or stroke.

What precautions apply to Ibuprofen?

Before using Ibudex, consider the following precautions. - Assess gastrointestinal risk: avoid use in patients with active peptic ulcer disease or history of GI bleeding. - Evaluate renal function: use cautiously in individuals with impaired kidney function or dehydration. - Monitor cardiovascular status: consider risk in patients with hypertension, heart failure, or coronary artery disease. - Review concomitant medications: avoid combining with other NSAIDs, anticoagulants, or corticosteroids without medical supervision. - Pregnancy and lactation: consult a healthcare professional before use during pregnancy or breastfeeding. - Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture and direct sunlight.

What does Ibuprofen interact with?

Ibuprofen can interact with other medicines; some combinations should be avoided while others require monitoring.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Corticosteroids: heightened risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce renal function. - SSRIs: potential for increased bleeding tendency.

Frequently asked questions

What is Ibudex used for?+
Ibudex contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain such as headache, dental pain, and musculoskeletal discomfort. It also reduces fever and helps manage inflammatory conditions like arthritis and dysmenorrhea. The product is intended for short‑term, over‑the‑counter use in adults and children as directed by a healthcare professional.
How does ibuprofen work?+
Ibuprofen works by non‑selectively blocking the cyclo‑oxygenase enzymes COX‑1 and COX‑2. This inhibition lowers the production of prostaglandins, which are chemicals that promote inflammation, pain, and fever. With fewer prostaglandins, the body experiences reduced swelling, less pain sensation, and a lowered temperature during febrile episodes.
What is the usual dose of Ibudex?+
The appropriate dose of Ibudex is determined by the prescribing healthcare professional based on the individual’s age, weight, and clinical condition. For adults, typical over‑the‑counter regimens range from 200 mg to 400 mg every four to six hours, not exceeding the maximum daily limit. Always follow the prescriber’s instructions or the label guidance.
Is Ibudex safe during pregnancy or breastfeeding?+
Safety of ibuprofen during pregnancy and lactation depends on the trimester and clinical circumstances. It is generally avoided in the third trimester because of potential fetal cardiovascular effects. During the first and second trimesters, use only if clearly needed and after consulting a healthcare provider. Ibuprofen passes into breast milk in small amounts; nursing mothers should seek medical advice before use.
How do I order Ibudex from GNH USA?+
To order Ibudex, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide. After the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any temperature requirements) and the necessary import documentation.
How does Ibudex compare with other NSAIDs?+
Ibudex (ibuprofen) shares the core NSAID properties of analgesia, antipyresis, and anti‑inflammation with agents such as naproxen or diclofenac. Compared with some longer‑acting NSAIDs, ibuprofen has a relatively short half‑life, which may allow flexible dosing but may require more frequent administration for sustained effect. Its safety profile is well‑characterised, though all NSAIDs share risks of gastrointestinal irritation and renal effects.
How should I store Ibudex?+
Ibudex should be stored at ambient temperature, preferably below 25 °C (77 °F). Keep the product in its original packaging, protect it from moisture, direct sunlight, and extreme heat. Do not store in bathrooms or near kitchen sinks where humidity is high. Keep out of reach of children.
How is Ibudex administered?+
Ibudex is taken orally with a glass of water. It may be taken with food or milk to lessen stomach discomfort, although it can also be taken on an empty stomach if tolerated. Swallow tablets whole; do not crush or chew unless the formulation specifically permits it. Follow the dosage instructions provided by the prescriber or the product label.
What are the most serious risks to watch for with Ibudex?+
Serious risks associated with ibuprofen include gastrointestinal bleeding or ulcer formation, especially in patients with a history of GI disease or when combined with anticoagulants. Kidney injury can occur in individuals with pre‑existing renal impairment or dehydration. Rare but severe allergic reactions such as anaphylaxis, as well as increased cardiovascular events (heart attack or stroke) in high‑risk patients, also warrant immediate medical attention.
Who should not use Ibudex?+
Ibudex should be avoided by individuals with known hypersensitivity to ibuprofen or any other NSAIDs, active peptic ulcer disease, severe heart failure, or uncontrolled hypertension. It is also contraindicated in patients taking certain anticoagulants, other NSAIDs, or corticosteroids without medical supervision. Pregnant women in the third trimester and patients with significant renal or hepatic impairment should not use the product unless directed by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ibuprofen
Route
Oral Use
Manufacturer
Dexcel Pharma Gmbh
Origin
EU

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