Ibu Biokanol

Ibuprofen, the active ingredient in Ibu Biokanol, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It relieves mild to moderate pain, reduces fever, and helps manage inflammatory conditions such as arthritis.

GNH USA supplies Ibu Biokanol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing consistent quality and adhering to EU manufacturing standards.

Ibuprofen is an NSAID that reduces inflammation and pain by inhibiting cyclooxygenase enzymes.

- Mild to moderate pain: provides relief from headaches, dental pain, and musculoskeletal aches. - Fever: lowers elevated body temperature associated with infections or inflammatory states. - Arthritis: decreases joint inflammation and improves mobility in osteoarthritis and rheumatoid arthritis. - Post‑operative pain: helps control discomfort after minor surgical procedures. - Menstrual cramps: alleviates dysmenorrhea‑related pain.

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain. - Headache: mild to moderate intensity. - Dizziness: transient sensation of light‑headedness. - Rash: mild skin erythema or itching.

Serious or Rare Side Effects: - Gastrointestinal bleeding: ulceration or hemorrhage in the stomach or intestines. - Renal impairment: reduced kidney function or acute kidney injury. - Hepatotoxicity: elevated liver enzymes or hepatitis. - Severe hypersensitivity: anaphylaxis, angioedema, or Stevens‑Johnson syndrome.

When using ibuprofen, several precautions should be observed to minimize risks. - Assess cardiovascular risk: avoid use in patients with uncontrolled hypertension or recent myocardial infarction. - Evaluate gastrointestinal history: use cautiously in those with ulcer disease or chronic NSAID use. - Monitor renal function: adjust use in patients with existing kidney impairment. - Limit use during pregnancy: avoid in the third trimester unless specifically directed. - Avoid concurrent anticoagulants: increased bleeding risk when combined with warfarin or similar agents. - Store at ambient temperature: keep below 25 °C in the original container, protected from moisture and direct sunlight.

Ibuprofen can interact with other medicines, altering their effectiveness or safety profile.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - High‑dose aspirin: heightened gastrointestinal toxicity. - Selective COX‑2 inhibitors: additive renal and cardiovascular adverse effects.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce antihypertensive response and affect kidney function. - Diuretics: potential for reduced diuretic efficacy and renal impairment. - Lithium: ibuprofen can increase lithium serum levels, risking toxicity.