Ibenal

Ibuprofen, the active ingredient in Ibenal, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats pain, fever and inflammation in adults and children as directed by a healthcare professional.

GNH USA supplies Ibenal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen is an NSAID that reduces pain, fever and inflammation by inhibiting prostaglandin synthesis.

Pain: provides relief of mild to moderate acute or chronic pain Fever: lowers elevated body temperature in febrile states Inflammation: decreases swelling associated with inflammatory conditions Arthritis: alleviates joint pain and stiffness in osteoarthritis and rheumatoid arthritis

Common Side Effects: - Gastrointestinal upset (nausea, dyspepsia) - Headache - Dizziness - Mild skin rash - Diarrhoea - Flatulence

Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding - Severe allergic reactions (anaphylaxis, angioedema) - Acute renal impairment - Hepatic injury - Cardiovascular thrombotic events - Stevens‑Johnson syndrome or toxic epidermal necrolysis

Before using Ibenal, consider the following precautions: - Assess renal function: evaluate kidney status prior to initiation - Monitor gastrointestinal risk: avoid in patients with a history of ulcer disease - Use the lowest effective dose: limit duration to reduce adverse events - Avoid in third‑trimester pregnancy: contraindicated due to fetal risks - Caution with anticoagulants: increased risk of bleeding - Store at ambient temperature: keep in the original container, protect from moisture and heat

Ibuprofen can interact with several medicines. Review the following before co‑administration.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened bleeding risk - Other NSAIDs: additive gastrointestinal toxicity - Corticosteroids: increased ulcer risk - ACE inhibitors or ARBs: potential reduction in renal function - Lithium: elevated serum lithium concentrations

Moderate Interactions (Monitor Closely): - Diuretics: possible renal effects - Methotrexate: reduced clearance leading to toxicity - SSRIs: increased bleeding tendency - Beta‑blockers: may blunt antihypertensive response - Cyclosporine: enhanced nephrotoxicity