GNH USA

Europe — EMA

Hypothiazid

GNH USA supplies Hypothiazid (Hydrochlorothiazide), a thiazide diuretic for hypertension and edema. Request a quote for global supply.

Hydrochlorothiazide

Request sourcing

1
Pack/s

What is Hydrochlorothiazide?

Hydrochlorothiazide, the active ingredient in Hypothiazid, is a thiazide diuretic presented as an oral tablet for oral use. It treats hypertension and edema in adults. GNH USA supplies Hypothiazid as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Hydrochlorothiazide used for?

Hydrochlorothiazide is indicated for conditions that involve fluid overload or elevated blood pressure.

- Hypertension: lowers systolic and diastolic blood pressure to reduce cardiovascular risk. - Edema associated with congestive heart failure: promotes urinary fluid loss to relieve peripheral swelling. - Edema due to renal disease: assists in removing excess extracellular fluid. - Edema secondary to liver cirrhosis: helps decrease ascites and peripheral edema.

What are the side effects of Hydrochlorothiazide?

Hydrochlorothiazide may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Increased urination - Low potassium levels (hypokalemia) - Dizziness - Headache

Serious or Rare Side Effects: - Severe dehydration - Acute gout attacks - Severe allergic reactions (anaphylaxis)

What precautions apply to Hydrochlorothiazide?

Before initiating therapy, clinicians should consider several safety measures.

- Monitor electrolytes: check serum potassium and sodium regularly. - Assess renal function: evaluate creatinine and eGFR before and during treatment. - Evaluate blood pressure: ensure adequate control without excessive hypotension. - Use with caution in diabetes: monitor glucose as thiazides may raise blood sugar. - Avoid abrupt discontinuation: taper if long‑term therapy is stopped. - Store at room temperature: keep in the original pack, protect from moisture.

What does Hydrochlorothiazide interact with?

Hydrochlorothiazide can alter the effects of several co‑administered medicines.

Major Interactions (Avoid): - Lithium: increased risk of lithium toxicity. - NSAIDs: may blunt the diuretic’s antihypertensive effect. - ACE inhibitors: heightened chance of severe hypotension.

Moderate Interactions (Monitor Closely): - Digoxin: altered serum concentrations may occur. - Alcohol: additive hypotensive effect, requiring caution.

Frequently asked questions

What is Hypothiazid used for?+
Hypothiazid contains hydrochlorothiazide, a thiazide diuretic that is prescribed to lower high blood pressure and to reduce fluid buildup (edema) associated with conditions such as congestive heart failure, renal disease, or liver cirrhosis. By promoting the excretion of excess salt and water, it helps control hypertension and relieve swelling.
How does hydrochlorothiazide work?+
Hydrochlorothiazide acts on the distal convoluted tubule of the kidney, where it blocks the sodium‑chloride symporter. This inhibition reduces reabsorption of sodium and chloride, leading to increased urinary loss of these ions together with water. The resulting decrease in plasma volume lowers blood pressure and diminishes tissue edema.
What is the usual dose of Hypothiazid?+
The exact dose of Hypothiazid is individualized by the prescribing clinician based on the patient’s condition, response, and renal function. Typical adult regimens start with a low dose and may be adjusted, but the specific strength and frequency should be determined by a qualified healthcare professional.
Is Hypothiazid safe during pregnancy or breastfeeding?+
Safety data for hydrochlorothiazide in pregnancy are limited, and the drug is generally classified as use‑only if the potential benefit justifies the risk to the fetus. It is excreted in breast milk, so nursing mothers should discuss alternatives with their physician before using Hypothiazid.
How do I order Hypothiazid from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity of Hypothiazid. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.
How does Hypothiazid compare with other antihypertensive diuretics?+
Compared with loop diuretics, hydrochlorothiazide is less potent for rapid fluid removal but is effective for long‑term blood‑pressure control and mild to moderate edema. It is often combined with other antihypertensives for synergistic effect, whereas loop diuretics are preferred in severe volume overload situations.
How should Hypothiazid be stored and handled?+
Hypothiazid tablets should be stored at room temperature, below 25 °C, in their original container to protect them from moisture and light. Keep the product out of reach of children and avoid storing in areas with high humidity or extreme heat.
How is Hypothiazid administered?+
Hypothiazid is taken orally, usually with a full glass of water. It can be taken with or without food, but consistent timing each day helps maintain stable blood levels. Patients should follow the dosing schedule prescribed by their healthcare provider.
What are the most serious risks to watch for while taking Hypothiazid?+
Serious adverse events include severe dehydration, acute gout attacks, and life‑threatening allergic reactions such as anaphylaxis. Patients should also be alert for signs of electrolyte imbalance, such as muscle cramps or irregular heartbeat, and seek medical attention promptly if these occur.
Who should not use Hypothiazid?+
Hypothiazid is contraindicated in patients with known hypersensitivity to hydrochlorothiazide or other thiazide diuretics. It should be used with caution in individuals with severe renal impairment, anuria, or a history of sulfonamide allergy, and it is generally avoided in pregnant women unless clearly indicated.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Hydrochlorothiazide
Route
Oral Use
Manufacturer
Sanofi Winthrop Industrie
Origin
EU

Related products

A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU
A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU
A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU
A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU