GNH USA

Europe — EMA

Hypericum Holland And Barrett

GNH USA supplies Hypericum Holland And Barrett (St. John's Wort), a herbal antidepressant for mild to moderate depression and seasonal affective disorder.

Dry Extract Of St. John's Wort (5-7:1), Extraction Solvent: Ethanol 60% V/V

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What is Dry Extract Of St. John's Wort (5-7:1), Extraction Solvent: Ethanol 60% V/V?

Hypericum perforatum (St. John's Wort) extract, the active ingredient in Hypericum Holland And Barrett, is a herbal antidepressant presented as a dry ethanol‑based extract (5‑7:1) for oral use. It is employed to support mood in adults with mild to moderate depressive symptoms and seasonal affective disorder, acting as a natural alternative to conventional antidepressants.

GNH USA supplies Hypericum Holland And Barrett as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide, providing consistent quality for global distribution.

What is Dry Extract Of St. John's Wort (5-7:1), Extraction Solvent: Ethanol 60% V/V used for?

Hypericum Holland And Barrett, a St. John's Wort extract, acts on neurotransmitter pathways associated with mood regulation.

- Mild to moderate depression: helps alleviate depressive symptoms and improve mood in adults. - Seasonal affective disorder: reduces winter‑related mood decline and associated fatigue. - Stress‑related mood disturbances: supports emotional balance during periods of heightened stress.

What are the side effects of Dry Extract Of St. John's Wort (5-7:1), Extraction Solvent: Ethanol 60% V/V?

Hypericum Holland And Barrett may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Gastrointestinal discomfort: nausea, stomach upset or diarrhoea. - Photosensitivity: increased sensitivity to sunlight leading to skin redness. - Dizziness or light‑headedness. - Fatigue or mild drowsiness. - Dry mouth.

Serious or Rare Side Effects: - Serotonin syndrome: potentially life‑threatening condition when combined with serotonergic drugs. - Severe allergic reactions: rash, itching, swelling, or anaphylaxis. - Manic or hypomanic episodes in susceptible individuals. - Significant liver enzyme elevation or hepatic injury.

What precautions apply to Dry Extract Of St. John's Wort (5-7:1), Extraction Solvent: Ethanol 60% V/V?

When considering Hypericum Holland And Barrett, several safety measures should be observed.

- Contraindicated in severe depression: not a substitute for professional psychiatric care. - Avoid concurrent use with SSRIs, MAO inhibitors or other serotonergic agents: risk of serotonin syndrome. - Caution in pregnancy and breastfeeding: safety not established; consult a healthcare provider. - Limit sun exposure: use protective clothing and sunscreen due to photosensitivity risk. - Monitor for mood switching: watch for signs of mania or hypomania. - Store at ambient temperature: keep in the original container, protect from moisture and direct light.

What does Dry Extract Of St. John's Wort (5-7:1), Extraction Solvent: Ethanol 60% V/V interact with?

Hypericum Holland And Barrett interacts with several medicines, requiring careful management.

Major Interactions (Avoid): - Selective serotonin reuptake inhibitors (SSRIs): may precipitate serotonin syndrome. - Monoamine oxidase inhibitors (MAOIs): risk of severe hypertensive reactions. - Warfarin: can reduce anticoagulant effect and increase bleeding risk.

Moderate Interactions (Monitor Closely): - Oral contraceptives: may decrease hormonal efficacy, leading to unintended pregnancy. - Anticonvulsants (e.g., carbamazepine, phenytoin): may lower plasma levels, reducing seizure control.

Frequently asked questions

What is Hypericum Holland And Barrett used for?+
Hypericum Holland And Barrett is an oral herbal supplement that contains a standardized dry extract of St. John's Wort. It is primarily used to support mood in adults experiencing mild to moderate depressive symptoms and to alleviate the low‑energy, low‑mood episodes associated with seasonal affective disorder.
How does St. John's Wort work?+
The extract of St. John's Wort contains bioactive compounds such as hypericin and hyperforin. These substances inhibit the reuptake of serotonin, dopamine and norepinephrine, increasing their levels in the brain, and also modulate GABA activity. The combined effect helps improve mood and reduce depressive symptoms.
What is the usual dose of Hypericum Holland And Barrett?+
The appropriate dose is determined by a qualified healthcare professional based on the individual’s condition, age, weight and other medications. Prescribers typically follow established dosing guidelines for St. John's Wort extracts, but the exact regimen should be confirmed with the treating clinician.
Is Hypericum Holland And Barrett safe during pregnancy or breastfeeding?+
Safety data for St. John's Wort during pregnancy and lactation are limited, and the product is generally not recommended for use in these periods. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss alternative options with their healthcare provider.
How do I order Hypericum Holland And Barrett from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.
How does Hypericum Holland And Barrett compare with conventional antidepressants?+
Unlike synthetic antidepressants such as SSRIs, Hypericum Holland And Barrett is a plant‑derived product that influences several neurotransmitter pathways simultaneously. It may have a milder side‑effect profile for some users, but it also carries a higher risk of drug‑drug interactions, especially with serotonergic agents, and its efficacy can be more variable.
What are the storage and handling requirements for this product?+
Store Hypericum Holland And Barrett at ambient temperature, preferably below 25 °C. Keep the container tightly closed, protect it from moisture and direct sunlight, and retain it in the original packaging until use to maintain product stability.
How is Hypericum Holland And Barrett administered?+
The product is taken orally, usually with a glass of water. It can be taken with or without food, but consistent administration with respect to meals may help reduce gastrointestinal discomfort. Patients should follow the dosing instructions provided by their prescriber.
What are the most serious risks associated with Hypericum Holland And Barrett?+
The most significant risks include the potential for serotonin syndrome when combined with other serotonergic drugs, severe photosensitivity leading to sunburn, and the possibility of triggering manic or hypomanic episodes in individuals with bipolar tendencies. Prompt medical attention is required if any of these serious reactions occur.
Who should not use Hypericum Holland And Barrett?+
Individuals taking SSRIs, MAO inhibitors, warfarin, oral contraceptives, or anticonvulsant medications should avoid or closely monitor use. It is also unsuitable for people with severe depression, those who are pregnant or breastfeeding, and patients with a history of photosensitivity or bipolar disorder without specialist guidance.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Dry Extract Of St. John's Wort (5-7:1), Extraction Solvent: Ethanol 60% V/V
Route
Oral Use
Manufacturer
Holland & Barrett Limited
Origin
EU

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