Europe — EMA
Hyoscine Injection Bp Ethypharm (Hyoscine Hydrobromide)
GNH USA supplies Hyoscine Bp Ethypharm (Hyoscine Hydrobromide), an antimuscarinic for smooth muscle spasm and secretion control.
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What is Hyoscine Hydrobromide?
Hyoscine Hydrobromide, the active ingredient in Hyoscine Injection Bp Ethypharm, is an antimuscarinic presented as an injectable solution for intramuscular or subcutaneous use. It reduces parasympathetic activity and is employed to alleviate smooth‑muscle spasm and control excessive secretions in surgical and gastrointestinal settings. It is indicated for pre‑operative and post‑operative management of gastrointestinal, biliary and urinary tract spasms, as well as for reduction of salivary and bronchial secretions.
GNH USA supplies Hyoscine Injection Bp Ethypharm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, clinics and procurement teams worldwide, ensuring consistent quality and regulatory compliance.
What is Hyoscine Hydrobromide used for?
Hyoscine Hydrobromide is an antimuscarinic agent used to manage conditions involving smooth‑muscle spasm and excessive secretions. - Pre‑operative or post‑operative smooth‑muscle spasm: reduces gastrointestinal, biliary and urinary tract spasms. - Surgical secretion control: decreases salivary, bronchial and gastric secretions during anesthesia. - Abdominal pain from spasm: alleviates pain associated with intestinal colic.
What are the side effects of Hyoscine Hydrobromide?
Hyoscine Injection may cause a range of adverse reactions, varying from mild to severe.
Common Side Effects: - Dry mouth: reduced salivation leading to throat discomfort. - Blurred vision: due to cycloplegia and pupil dilation. - Tachycardia: increased heart rate without underlying arrhythmia. - Urinary retention: difficulty initiating or maintaining voiding. - Constipation: slowed gastrointestinal motility. - Dizziness: light‑headed sensation, especially on standing.
Serious or Rare Side Effects: - Anaphylactic reaction: severe allergy with rash, swelling and respiratory compromise. - Acute angle‑closure glaucoma: sudden eye pain and visual loss. - Delirium or hallucinations: altered mental status, especially in elderly. - Severe tachyarrhythmia: potentially life‑threatening rapid heart rhythms. - Hypotension: marked drop in blood pressure causing faintness.
What precautions apply to Hyoscine Hydrobromide?
Before administering Hyoscine Injection, clinicians should evaluate patient risk factors and monitor for specific contraindications. - Cardiac assessment: avoid in patients with tachyarrhythmias or severe heart block. - Glaucoma caution: contraindicated in narrow‑angle glaucoma due to risk of acute closure. - Urinary tract considerations: use with caution in patients with urinary retention or prostatic hypertrophy. - Elderly monitoring: increased susceptibility to confusion, delirium and anticholinergic toxicity. - Pregnancy and lactation: safety not established; prescribe only when benefit outweighs potential risk. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.
What does Hyoscine Hydrobromide interact with?
Hyoscine Hydrobromide can interact with other medications, altering its anticholinergic profile or enhancing adverse effects.
Major Interactions (Avoid): - Other anticholinergics (e.g., atropine, scopolamine patches): additive anticholinergic burden. - Tricyclic antidepressants: increased risk of severe anticholinergic side effects. - Antihistamines with strong anticholinergic activity: heightened sedation and dry mouth.
Moderate Interactions (Monitor Closely): - Opioids: may potentiate sedation and respiratory depression. - Alcohol: can exacerbate dizziness, confusion and hypotension. - Diuretics: may worsen urinary retention.



